Radiation therapy‐associated toxicity: Etiology, management, and prevention

K Wang, JE Tepper - CA: a cancer journal for clinicians, 2021 - Wiley Online Library
Radiation therapy (RT) is a curative treatment for many malignancies and provides effective
palliation in patients with tumor‐related symptoms. However, the biophysical effects of RT …

The changing therapeutic landscape of head and neck cancer

JD Cramer, B Burtness, QT Le, RL Ferris - Nature reviews Clinical …, 2019 - nature.com
Head and neck cancers are a heterogeneous collection of malignancies of the upper
aerodigestive tract, salivary glands and thyroid. In this Review, we primarily focus on the …

Treatment of late sequelae after radiotherapy for head and neck cancer

P Strojan, KA Hutcheson, A Eisbruch, JJ Beitler… - Cancer treatment …, 2017 - Elsevier
Radiotherapy (RT) is used to treat approximately 80% of patients with cancer of the head
and neck. Despite enormous advances in RT planning and delivery, a significant number of …

Head and neck cancer: improving outcomes with a multidisciplinary approach

C Lo Nigro, N Denaro, A Merlotti… - Cancer management and …, 2017 - Taylor & Francis
For early-stage head and neck cancer (HNC), surgery (S) or radiotherapy (RT) is a standard
treatment. The multidisciplinary approach, which includes multimodality treatment with S …

Increase in head and neck cancer in younger patients due to human papillomavirus (HPV)

D Young, CC Xiao, B Murphy, M Moore, C Fakhry… - Oral oncology, 2015 - Elsevier
The face of head and neck cancer has changed dramatically over the past 30 years. There
has been a steady decline in the number of tobacco and alcohol related squamous cell …

Functional outcomes after TORS for oropharyngeal cancer: a systematic review

KA Hutcheson, FC Holsinger, ME Kupferman… - European Archives of …, 2015 - Springer
Summarize functional outcomes after transoral robotic surgery (TORS)±adjuvant therapy for
oropharyngeal cancer (OPC). A systematic review was conducted. The MEDLINE database …

Sparing the region of the salivary gland containing stem cells preserves saliva production after radiotherapy for head and neck cancer

P Van Luijk, S Pringle, JO Deasy… - Science translational …, 2015 - science.org
Each year, 500,000 patients are treated with radiotherapy for head and neck cancer,
resulting in relatively high survival rates. However, in 40% of patients, quality of life is …

Eat and exercise during radiotherapy or chemoradiotherapy for pharyngeal cancers: use it or lose it

KA Hutcheson, MK Bhayani, BM Beadle… - … –head & neck …, 2013 - jamanetwork.com
Importance Data support proactive swallowing therapy during radiotherapy (RT) or
chemoradiotherapy (CRT) for pharyngeal cancers. The benefits of adherence to a regimen …

Mature results of a prospective study of deintensified chemoradiotherapy for low‐risk human papillomavirus‐associated oropharyngeal squamous cell carcinoma

BS Chera, RJ Amdur, JE Tepper, X Tan, J Weiss… - Cancer, 2018 - Wiley Online Library
BACKGROUND The purpose of the current study was to determine quality of life and tumor
control from a prospective phase 2 clinical trial evaluating deintensified chemoradiotherapy …

Chemo-IMRT of oropharyngeal cancer aiming to reduce dysphagia: swallowing organs late complication probabilities and dosimetric correlates

A Eisbruch, HM Kim, FY Feng, TH Lyden… - International Journal of …, 2011 - Elsevier
PURPOSE: Assess dosimetric correlates of long-term dysphagia after chemo-intensity-
modulated radiotherapy (IMRT) of oropharyngeal cancer (OPC) sparing parts of the …