[HTML][HTML] Diuretic effects of Hecogenin and Hecogenin acetate via aldosterone synthase inhibition
Hecogenin (HEC) is a steroidal saponin found in many plant species and serves as a
precursor for steroidal drugs. The diuretic effects of HEC and its derivative, hecogenin …
precursor for steroidal drugs. The diuretic effects of HEC and its derivative, hecogenin …
Network pharmacology and molecular docking: combined computational approaches to explore the antihypertensive potential of Fabaceae species
Hypertension is a major global public health issue, affecting quarter of adults worldwide.
Numerous synthetic drugs are available for treating hypertension; however, they often come …
Numerous synthetic drugs are available for treating hypertension; however, they often come …
Genetic Factors Contributing to the Pathogenesis of Essential Hypertension in Two African Populations
K Kalideen, B Rayner, R Ramesar - Journal of Personalized Medicine, 2024 - mdpi.com
The African continent has the highest prevalence of hypertension globally, with South Africa
reporting the highest prevalence in Southern Africa. While the influence of genetic variability …
reporting the highest prevalence in Southern Africa. While the influence of genetic variability …
Pharmacogenomic Study of Selected Genes Affecting Amlodipine Blood Pressure Response in Patients with Hypertension
A Jan, AR Alanzi, RA Mothana, JY Kaimori… - Pharmacogenomics …, 2024 - Taylor & Francis
Introduction Despite the availability of various antihypertensive medications, the response to
these medications varies among individuals. Understanding how individual genetic …
these medications varies among individuals. Understanding how individual genetic …
Association of combined− 344T/C and K173R polymorphisms in aldosterone synthase gene with type 2 diabetes mellitus in the Moroccan population.
Y Nouhi, FZ Aboubakr, O El Brini… - Romanian Journal of …, 2024 - sciendo.com
Background: Aldosterone synthase (CYP11B2) is crucial for aldosterone production, and
variations in its gene may influence type 2 diabetes mellitus (T2DM) development. This …
variations in its gene may influence type 2 diabetes mellitus (T2DM) development. This …
Влияние полиморфизма C-344T гена альдостерон синтазы на вариабельность антигипертензивной терапии блокаторами рецептора ангиотензина II …
ЕВ Реброва, ЕВ Ших, НБ Лазарева - Фармация и фармакология, 2024 - pharmpharm.ru
Аннотация Эффективность антигипертензивной терапии может быть ассоциирована с
генетическими факторами, которые влияют не только на степень повышения …
генетическими факторами, которые влияют не только на степень повышения …