An update on diagnostic and prognostic biomarkers for traumatic brain injury
Introduction: Traumatic brain injury (TBI) is a major worldwide neurological disorder of
epidemic proportions. To date, there are still no FDA-approved therapies to treat any forms …
epidemic proportions. To date, there are still no FDA-approved therapies to treat any forms …
A literature review of traumatic brain injury biomarkers
Research into TBI biomarkers has accelerated rapidly in the past decade owing to the
heterogeneous nature of TBI pathologies and management, which pose challenges to TBI …
heterogeneous nature of TBI pathologies and management, which pose challenges to TBI …
A review of the clinical utility of serum S100B protein levels in the assessment of traumatic brain injury
EP Thelin, DW Nelson, BM Bellander - Acta neurochirurgica, 2017 - Springer
Background In order to improve injury assessment of brain injuries, protein markers of
pathophysiological processes and tissue fate have been introduced in the clinic. The most …
pathophysiological processes and tissue fate have been introduced in the clinic. The most …
A review of magnetic resonance imaging and diffusion tensor imaging findings in mild traumatic brain injury
Mild traumatic brain injury (mTBI), also referred to as concussion, remains a controversial
diagnosis because the brain often appears quite normal on conventional computed …
diagnosis because the brain often appears quite normal on conventional computed …
Military traumatic brain injury: a challenge straddling neurology and psychiatry
LZ Kong, RL Zhang, SH Hu, JB Lai - Military medical research, 2022 - Springer
Military psychiatry, a new subcategory of psychiatry, has become an invaluable, intangible
effect of the war. In this review, we begin by examining related military research …
effect of the war. In this review, we begin by examining related military research …
Serum levels of ubiquitin C-terminal hydrolase distinguish mild traumatic brain injury from trauma controls and are elevated in mild and moderate traumatic brain injury …
L Papa, LM Lewis, S Silvestri, JL Falk… - Journal of Trauma …, 2012 - journals.lww.com
BACKGROUND: This study compared early serum levels of ubiquitin C-terminal hydrolase
(UCH-L1) from patients with mild and moderate traumatic brain injury (TBI) with uninjured …
(UCH-L1) from patients with mild and moderate traumatic brain injury (TBI) with uninjured …
Therapy development for diffuse axonal injury
DH Smith, R Hicks, JT Povlishock - Journal of neurotrauma, 2013 - liebertpub.com
Diffuse axonal injury (DAI) remains a prominent feature of human traumatic brain injury (TBI)
and a major player in its subsequent morbidity. The importance of this widespread axonal …
and a major player in its subsequent morbidity. The importance of this widespread axonal …
Human traumatic brain injury induces autoantibody response against glial fibrillary acidic protein and its breakdown products
Z Zhang, JS Zoltewicz, S Mondello, KJ Newsom… - PloS one, 2014 - journals.plos.org
The role of systemic autoimmunity in human traumatic brain injury (TBI) and other forms of
brain injuries is recognized but not well understood. In this study, a systematic investigation …
brain injuries is recognized but not well understood. In this study, a systematic investigation …
Clinical utility of serum levels of ubiquitin C-terminal hydrolase as a biomarker for severe traumatic brain injury
BACKGROUND: Brain damage markers released in cerebrospinal fluid (CSF) and blood
may provide valuable information about diagnosis and outcome prediction after traumatic …
may provide valuable information about diagnosis and outcome prediction after traumatic …
Biokinetic analysis of ubiquitin C-terminal hydrolase-L1 (UCH-L1) in severe traumatic brain injury patient biofluids
Ubiquitin C-terminal hydrolase-L1 (UCH-L1) is a neuron-specific enzyme that has been
identified as a potential biomarker of traumatic brain injury (TBI). The study objectives were …
identified as a potential biomarker of traumatic brain injury (TBI). The study objectives were …