[HTML][HTML] Tendon tissue engineering: Cells, growth factors, scaffolds and production techniques

S Ruiz-Alonso, M Lafuente-Merchan, J Ciriza… - Journal of Controlled …, 2021 - Elsevier
Tendon injuries are a global health problem that affects millions of people annually. The
properties of tendons make their natural rehabilitation a very complex and long-lasting …

TGF-β and mesenchymal stromal cells in regenerative medicine, autoimmunity and cancer

V de Araújo Farias, AB Carrillo-Gálvez, F Martin… - Cytokine & Growth …, 2018 - Elsevier
Multipotent mesenchymal stromal cells (MSCs) represent a promising cell-based therapy in
regenerative medicine and for the treatment of inflammatory/autoimmune diseases …

Bone marrow mesenchymal stem cell-derived exosomes promote tendon regeneration by facilitating the proliferation and migration of endogenous tendon stem …

H Yu, J Cheng, W Shi, B Ren, F Zhao, Y Shi, P Yang… - Acta biomaterialia, 2020 - Elsevier
Mesenchymal stem cells (MSCs)-derived exosomes are being increasingly focused as the
new biological pro-regenerative therapeutic agents for various types of tissue injury. Here …

[HTML][HTML] In vitro innovation of tendon tissue engineering strategies

MR Citeroni, MC Ciardulli, V Russo… - International journal of …, 2020 - mdpi.com
Tendinopathy is the term used to refer to tendon disorders. Spontaneous adult tendon
healing results in scar tissue formation and fibrosis with suboptimal biomechanical …

Braided and stacked electrospun nanofibrous scaffolds for tendon and ligament tissue engineering

BB Rothrauff, BB Lauro, G Yang, RE Debski… - … Engineering Part A, 2017 - liebertpub.com
Tendon and ligament injuries are a persistent orthopedic challenge given their poor innate
healing capacity. Nonwoven electrospun nanofibrous scaffolds composed of polyesters …

Engineered cell sheets for the effective delivery of adipose-derived stem cells for tendon-to-bone healing

MJ Shin, IK Shim, DM Kim, JH Choi… - … American journal of …, 2020 - journals.sagepub.com
Background: Efforts are being made to treat rotator cuff tears (RCTs) that exhibit poor
healing and high retear rates. Tendon-to-bone healing using mesenchymal stem cells is …

Development and maintenance of tendons and ligaments

L Bobzin, RR Roberts, HJ Chen, JG Crump… - …, 2021 - journals.biologists.com
Tendons and ligaments are fibrous connective tissues vital to the transmission of force and
stabilization of the musculoskeletal system. Arising in precise regions of the embryo …

Mechanical activation drives tenogenic differentiation of human mesenchymal stem cells in aligned dense collagen hydrogels

H Park, SN Nazhat, DH Rosenzweig - Biomaterials, 2022 - Elsevier
Tendons are force transmitting mechanosensitive tissues predominantly comprised of highly
aligned collagen type I fibres. In this study, the recently introduced gel aspiration-ejection …

Mechanically and biologically promoted cell-laden constructs generated using tissue-specific bioinks for tendon/ligament tissue engineering applications

S Chae, YJ Choi, DW Cho - Biofabrication, 2022 - iopscience.iop.org
Tendon and ligament tissues provide stability and mobility crucial for musculoskeletal
function, but are particularly prone to injury. Owing to poor innate healing capacity, the …

Long noncoding RNA H19 accelerates tenogenic differentiation and promotes tendon healing through targeting miR‐29b‐3p and activating TGF‐β1 signaling

YF Lu, Y Liu, WM Fu, J Xu, B Wang, YX Sun… - The FASEB …, 2017 - Wiley Online Library
Tendon injures are common orthopedic conditions, but tendon development and the
pathogenesis of tendon injures, such as tendinopathy, remain largely unknown and have …