Although the endothelium has a number of important functions, the term endothelial
dysfunction is commonly used to describe impairment in its vasodilatory capacity. It is …

Essential hypertension is associated with endothelial dysfunction, which is caused mainly by
the production of oxygen-free radicals that can destroy nitric oxide (NO), and impair its …

Background—Forearm endothelial dysfunction, characterized by an impaired vasodilating
response to acetylcholine (ACh), may be associated with several cardiovascular risk factors …

A large body of evidence indicates that patients with essential hypertension are
characterized by endothelial dysfunction mediated by an impaired NO availability secondary …

Objectives: This study sought to investigate whether pulse pressure (PP) is associated with
endothelium-dependent vasodilation in a group of never-treated hypertensives …

The endothelium is more than just a passive interface between the blood and the vessel
wall. Since the pioneering discovery of nitric oxide as an important endothelium-derived …

The vascular endothelium plays a fundamental role in the basal and dynamic regulation of
the circulation. Thus, it has a crucial role in the pathogenesis of hypertension. A spectrum of …

Both endothelial and platelet-derived nitric oxide have important vasculoprotective
properties. Increasing evidence suggests a dysfunctional platelet nitric oxide synthase type …

This brief review discusses the ways, if and when available, to examine endothelium-
dependent changes in diameter in human blood vessels. It stresses the problems in …

The vascular endothelium synthesizes and releases a spectrum of vasoactive substances
like nitric oxide (NO) and endothelin (ET). In hypertension, the delicate balance of …