Archaea are microorganisms more closely related to eukaryotes than bacteria. Almost 50
years after being defined as a new domain of life on earth, new species continue to be …

This review is a first attempt to overview both medical and industrial applications of
bisphosphonates (BPs) at once, with an emphasis on structure–property relationships. The …

Breast cancer has a poor prognosis due to the toxic side effects associated with high doses
of chemotherapy. Liposomal drug encapsulation has resulted in clinical success in …

Bacterioruberin (BR) is a dipolar C50 isoprenoid with 13 conjugated double bonds and four
terminals hydroxyl groups produced by most members of the Haloferacaceae family of …

The anti-inflammatory, antifibrotic and antimicrobial activities of curcumin (CUR) are missed
because of its low solubility in aqueous media, low bioavailability, and structural lability …

Wear particles of ultra-high molecular weight polyethylene (UHMWPE) are inevitable during
service as joint prosthesis, and particles≤ 10 μm with critical size could cause serious …

This study aimed to determine the damage mechanisms caused by naturally targeted
nanoarchaeosomes made of diether lipids from Halorubrum tebenquichense loaded with …

Neutral and positively charged archaeal ether lipids (AEL) have been studied for their
utilization as novel delivery systems for pDNA, showing efficient immune response with a …

Sodium alendronate (ALN) is a very hydrosoluble and poorly permeable molecule used as
an antiresorptive agent and with vascular anticalcifying capacity. Loaded into targeted …

Background The wide spectrum of antitumoral mechanisms of imiquimod (IMQ), made it a
good candidate for topical therapy of melanoma. However, physicochemical properties …