A brief history of protein sorting prediction

H Nielsen, KD Tsirigos, S Brunak, G von Heijne - The protein journal, 2019 - Springer
Ever since the signal hypothesis was proposed in 1971, the exact nature of signal peptides
has been a focus point of research. The prediction of signal peptides and protein subcellular …

[HTML][HTML] Recent advances in developing web-servers for predicting protein attributes

KC Chou, HB Shen - Natural science, 2009 - scirp.org
Recent advance in large-scale genome se-quencing has generated a huge volume of pro-
tein sequences. In order to timely utilize the in-formation hidden in these newly discovered …

Improved prediction of signal peptides: SignalP 3.0

JD Bendtsen, H Nielsen, G Von Heijne… - Journal of molecular …, 2004 - Elsevier
We describe improvements of the currently most popular method for prediction of classically
secreted proteins, SignalP. SignalP consists of two different predictors based on neural …

Prediction of protein subcellular localization

CS Yu, YC Chen, CH Lu… - … : Structure, Function, and …, 2006 - Wiley Online Library
Because the protein's function is usually related to its subcellular localization, the ability to
predict subcellular localization directly from protein sequences will be useful for inferring …

Predicting subcellular localization of proteins for Gram‐negative bacteria by support vector machines based on n‐peptide compositions

CS Yu, CJ Lin, JK Hwang - Protein science, 2004 - Wiley Online Library
Gram‐negative bacteria have five major subcellular localization sites: the cytoplasm, the
periplasm, the inner membrane, the outer membrane, and the extracellular space. The …

Cell-PLoc: a package of Web servers for predicting subcellular localization of proteins in various organisms

KC Chou, HB Shen - Nature protocols, 2008 - nature.com
Abstract Information on subcellular localization of proteins is important to molecular cell
biology, proteomics, system biology and drug discovery. To provide the vast majority of …

AlgPred: prediction of allergenic proteins and mapping of IgE epitopes

S Saha, GPS Raghava - Nucleic acids research, 2006 - academic.oup.com
In this study a systematic attempt has been made to integrate various approaches in order to
predict allergenic proteins with high accuracy. The dataset used for testing and training …

Learning with multiclass AUC: Theory and algorithms

Z Yang, Q Xu, S Bao, X Cao… - IEEE Transactions on …, 2021 - ieeexplore.ieee.org
The Area under the ROC curve (AUC) is a well-known ranking metric for problems such as
imbalanced learning and recommender systems. The vast majority of existing AUC …

A multi-label classifier for predicting the subcellular localization of gram-negative bacterial proteins with both single and multiple sites

X Xiao, ZC Wu, KC Chou - PloS one, 2011 - journals.plos.org
Prediction of protein subcellular localization is a challenging problem, particularly when the
system concerned contains both singleplex and multiplex proteins. In this paper, by …

[HTML][HTML] Cell-PLoc 2.0: an improved package of web-servers for predicting subcellular localization of proteins in various organisms

KC Chou, HB Shen - Natural Science, 2010 - scirp.org
Cell-PLoc 2.0 is a package of web-servers evolved from Cell-PLoc (Chou, KC & Shen, HB,
Nature Protocols, 2008, 2: 153-162) by a top-down approach to improve the power for …