Biological concepts for catalysis and reactivity: empowering bioinspiration
Biological systems provide attractive reactivity blueprints for the design of challenging
chemical transformations. Emulating the operating mode of natural systems may however …
chemical transformations. Emulating the operating mode of natural systems may however …
A Series of Ni Complexes Based on a Versatile ATCUN-Like Tripeptide Scaffold to Decipher Key Parameters for Superoxide Dismutase Activity
J Domergue, P Guinard, M Douillard, J Pécaut… - Inorganic …, 2023 - ACS Publications
The cellular level of reactive oxygen species (ROS) has to be controlled to avoid some
pathologies, especially those linked to oxidative stress. One strategy for designing …
pathologies, especially those linked to oxidative stress. One strategy for designing …
A Bioinspired NiII Superoxide Dismutase Catalyst Designed on an ATCUN-like Binding Motif
J Domergue, P Guinard, M Douillard, J Pecaut… - Inorganic …, 2021 - ACS Publications
Nickel superoxide dismutase (NiSOD) is an enzyme that protects cells against O2·–. While
the structure of its active site is known, the mechanism of the catalytic cycle is still not …
the structure of its active site is known, the mechanism of the catalytic cycle is still not …
[HTML][HTML] Reduction-cleavable desferrioxamine B pulldown system enriches Ni (ii)-superoxide dismutase from a Streptomyces proteome
Two resins with the hydroxamic acid siderophore desferrioxamine B (DFOB) immobilised as
a free ligand or its Fe (III) complex were prepared to screen the Streptomyces pilosus …
a free ligand or its Fe (III) complex were prepared to screen the Streptomyces pilosus …
Mononuclear Ni (II) Complexes with a S3O Coordination Sphere Based on a Tripodal Cysteine-Rich Ligand: pH Tuning of the Superoxide Dismutase Activity
J Domergue, J Pécaut, O Proux, C Lebrun… - Inorganic …, 2019 - ACS Publications
The superoxide dismutase (SOD) activity of mononuclear NiII complexes, whose structures
are inspired by the NiSOD, has been investigated. They have been designed with a sulfur …
are inspired by the NiSOD, has been investigated. They have been designed with a sulfur …
A comparative study on the nickel binding ability of peptides containing separate cysteinyl residues
G Szunyog, A Laskai, D Szűcs, I Sóvágó… - Dalton …, 2019 - pubs.rsc.org
Nickel (II) complexes of peptides CSSACS-NH2, ACSSACS-NH2, SSCSSACS-NH2 and
GACAAH-NH2 have been studied by potentiometric and various spectroscopic (UV-vis, CD …
GACAAH-NH2 have been studied by potentiometric and various spectroscopic (UV-vis, CD …
[HTML][HTML] pH Dependent Reversible Formation of a Binuclear Ni2 Metal-Center within a Peptide Scaffold
BC Keegan, D Ocampo, J Shearer - Inorganics, 2019 - mdpi.com
A disulfide-bridged peptide containing two Ni2+ binding sites based on the nickel
superoxide dismutase protein,{Ni2 (SODmds)} has been prepared. At physiological pH (7.4) …
superoxide dismutase protein,{Ni2 (SODmds)} has been prepared. At physiological pH (7.4) …
Chemical synthesis of switchable peptide-based nanopores: from ion channels to bio-inspired materials
L Mueller - 2019 - tuprints.ulb.tu-darmstadt.de
The generation of different types of peptide-based nanopores is elucidated in this work. First,
biological nanopores are investigated. Ion channels and pore-forming proteins represent an …
biological nanopores are investigated. Ion channels and pore-forming proteins represent an …
[PDF][PDF] Chemical Biology
H Li, W Dingb, Q Zhang - 2024 - researchgate.net
RSC Chem. Biol.© 2023 The Author (s). Published by the Royal Society of Chemistry
genome mining is playing an increasingly important role in RiPP discovery. 6, 11, 12 …
genome mining is playing an increasingly important role in RiPP discovery. 6, 11, 12 …
[引用][C] Catalytic Domino reactions for the ecologically and economically favorable synthesis of natural products and materials
LF Tietze - Advances in synthesis and complexing, 2019 - elibrary.ru