[HTML][HTML] ST-GEARS: Advancing 3D downstream research through accurate spatial information recovery

T Xia, L Hu, L Zuo, L Cao, Y Zhang, M Xu, Q Lu… - Nature …, 2024 - nature.com
Abstract Three-dimensional Spatial Transcriptomics has revolutionized our understanding of
tissue regionalization, organogenesis, and development. However, existing approaches …

[HTML][HTML] Analysis of synthetic cellular barcodes in the genome and transcriptome with BARtab and bartools

H Holze, L Talarmain, KA Fennell, EY Lam… - Cell Reports …, 2024 - cell.com
Cellular barcoding is a lineage-tracing methodology that couples heritable synthetic
barcodes to high-throughput sequencing, enabling the accurate tracing of cell lineages …

CellBin: a highly accurate single-cell gene expression processing pipeline for high-resolution spatial transcriptomics

M Li, H Liu, Q Kang, S Fang, M Li, J Zhang, F Teng… - Biorxiv, 2023 - biorxiv.org
Background Owing to recent advances in resolution and field-of-view, spatially resolved
transcriptomics sequencing, such as Stereo-seq, has emerged as a cutting-edge technology …

[HTML][HTML] Spatial Dissection of the Distinct Cellular Responses to Normal Aging and Alzheimer's Disease in Human Prefrontal Cortex at Single-Nucleus Resolution

Y Gong, M Haeri, X Zhang, Y Li, A Liu, D Wu, Q Zhang… - medRxiv, 2024 - ncbi.nlm.nih.gov
Aging significantly elevates the risk for Alzheimer's disease (AD), contributing to the
accumulation of AD pathologies, such as amyloid-β (Aβ), inflammation, and oxidative stress …

[HTML][HTML] Generating single-cell gene expression profiles for high-resolution spatial transcriptomics based on cell boundary images

B Zhang, M Li, Q Kang, Z Deng, H Qin, K Su, X Feng… - Gigabyte, 2024 - ncbi.nlm.nih.gov
In spatially resolved transcriptomics, Stereo-seq facilitates the analysis of large tissues at the
single-cell level, offering subcellular resolution and centimeter-level field-of-view. Our …

CellBin: a highly accurate single-cell gene expression processing pipeline for high-resolution spatial transcriptomics

M Li, H Liu, Q Kang, S Fang, M Li, J Zhang, F Teng… - bioRxiv, 2024 - biorxiv.org
Background Owing to recent advances in resolution and field-of-view, spatially resolved
transcriptomics sequencing, such as Stereo-seq, has emerged as a cutting-edge technology …