Physiological signaling functions of reactive oxygen species in stem cells: from flies to man

SA Sinenko, TY Starkova, AA Kuzmin… - Frontiers in cell and …, 2021 - frontiersin.org
Reactive oxygen species (ROS), superoxide anion and hydrogen peroxide, are generated
as byproducts of oxidative phosphorylation in the mitochondria or via cell signaling-induced …

The role of antioxidants in the chemistry of oxidative stress: A review

AM Pisoschi, A Pop - European journal of medicinal chemistry, 2015 - Elsevier
Abstract This Review Article is focused on the action of the reactive oxygenated species in
inducing oxidative injury of the lipid membrane components, as well as on the ability of …

Redox homeostasis and mitochondrial dynamics

PHGM Willems, R Rossignol, CEJ Dieteren… - Cell metabolism, 2015 - cell.com
Within living cells, mitochondria are considered relevant sources of reactive oxygen species
(ROS) and are exposed to reactive nitrogen species (RNS). During the last decade …

The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response

BN Puente, W Kimura, SA Muralidhar, J Moon… - Cell, 2014 - cell.com
The mammalian heart has a remarkable regenerative capacity for a short period of time after
birth, after which the majority of cardiomyocytes permanently exit cell cycle. We sought to …

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

AP West, IE Brodsky, C Rahner, DK Woo… - Nature, 2011 - nature.com
Reactive oxygen species (ROS) are essential components of the innate immune response
against intracellular bacteria and it is thought that professional phagocytes generate ROS …

Mitochondria in innate immune responses

AP West, GS Shadel, S Ghosh - Nature Reviews Immunology, 2011 - nature.com
The innate immune system has a key role in the mammalian immune response. Recent
research has demonstrated that mitochondria participate in a broad range of innate immune …

Interactions between mitochondrial reactive oxygen species and cellular glucose metabolism

DC Liemburg-Apers, PHGM Willems… - Archives of …, 2015 - Springer
Mitochondrial reactive oxygen species (ROS) production and detoxification are tightly
balanced. Shifting this balance enables ROS to activate intracellular signaling and/or induce …

Fluorescent molecular rotors for viscosity sensors

SC Lee, J Heo, HC Woo, JA Lee… - … A European Journal, 2018 - Wiley Online Library
Fluorescent molecular rotors (FMRs) can act as viscosity sensors in various media including
subcellular organelles and microfluidic channels. In FMRs, the rotation of rotators connected …

The bioactivity and toxicological actions of carvacrol

ZE Suntres, J Coccimiglio, M Alipour - Critical reviews in food …, 2015 - Taylor & Francis
Carvacrol is a monoterpenic phenol produced by an abundant number of aromatic plants,
including thyme and oregano. Presently, carvacrol is used in low concentrations as a food …

Redox regulation of mitochondrial function

DE Handy, J Loscalzo - Antioxidants & redox signaling, 2012 - liebertpub.com
Redox-dependent processes influence most cellular functions, such as differentiation,
proliferation, and apoptosis. Mitochondria are at the center of these processes, as …