[HTML][HTML] Hydroxycinnamic acids and their derivatives: Cosmeceutical significance, challenges and future perspectives, a review

O Taofiq, AM González-Paramás, MF Barreiro… - Molecules, 2017 - mdpi.com
Bioactive compounds from natural sources, due to their widely-recognized benefits, have
been exploited as cosmeceutical ingredients. Among them, phenolic acids emerge with a …

Crocin inhibits oxidative stress and pro-inflammatory response of microglial cells associated with diabetic retinopathy through the activation of PI3K/Akt signaling …

X Yang, F Huo, B Liu, J Liu, T Chen, J Li, Z Zhu… - Journal of Molecular …, 2017 - Springer
Diabetic retinopathy (DR) is a serious microvascular complication of diabetes mellitus that is
closely associated with the degeneration and loss of retinal ganglion cells (RGCs) caused …

[HTML][HTML] Procyanidin A1 Alleviates Inflammatory Response induced by LPS through NF-κB, MAPK, and Nrf2/HO-1 Pathways in RAW264. 7 cells

S Han, H Gao, S Chen, Q Wang, X Li, LJ Du, J Li… - Scientific reports, 2019 - nature.com
Inflammation is a complex physiological process that poses a serious threat to people's
health. However, the potential molecular mechanisms of inflammation are still not clear …

Dopamine regulates cytokine secretion during innate and adaptive immune responses

M Kawano, R Takagi, K Saika, M Matsui… - International …, 2018 - academic.oup.com
Dopamine (DA) is synthesized by various immune cells. DA receptors (DARs), which
comprise five isoforms, are expressed on the surface of these cells. Therefore, it is likely that …

Unravelling the anti-inflammatory mechanism of Allium cepa: an integration of network pharmacology and molecular docking approaches

V Omoboyede, OS Onile, BF Oyeyemi, RT Aruleba… - Molecular Diversity, 2024 - Springer
Allium cepa, commonly known as onion, is a widely consumed spice that possesses
numerous pharmacological properties. A. cepa bioactive components are often explored in …

Anti-inflammatory effect of tranexamic acid against trauma-hemorrhagic shock-induced acute lung injury in rats

Y Teng, C Feng, Y Liu, H Jin, Y Gao, T Li - Experimental animals, 2018 - jstage.jst.go.jp
It has been demonstrated that tranexamic acid (TXA), a synthetic derivative of lysine,
alleviates lung damage in a trauma-hemorrhagic shock (T/HS) model. Nevertheless, the …

Eckol from Eisenia bicyclis Inhibits Inflammation Through the Akt/NF‐κB Signaling in Propionibacterium acnes‐Induced Human Keratinocyte Hacat Cells

SH Eom, EH Lee, K Park, JY Kwon… - Journal of Food …, 2017 - Wiley Online Library
To investigate whether eckol, a phlorotannin compound from edible brown seaweed Eisenia
bicyclis, could be responsible for the suppression of inflammatory processes, we examined …

[HTML][HTML] Anti-Inflammatory Activity of Populus deltoides Leaf Extract via Modulating NF-κB and p38/JNK Pathways

YE Jeong, MY Lee - International Journal of Molecular Sciences, 2018 - mdpi.com
Populus deltoides, known as eastern cottonwood, has been commonly used as a medicinal
plant. The aim of the present study was to investigate the mechanism underlying the anti …

[HTML][HTML] Synergistic Pulmonoprotective Effect of Natural Prolyl Oligopeptidase Inhibitors in In Vitro and In Vivo Models of Acute Respiratory Distress Syndrome

S Zerikiotis, P Efentakis, D Dapola, A Agapaki… - International Journal of …, 2023 - mdpi.com
Acute respiratory distress syndrome (ARDS) is a highly morbid inflammatory lung disease
with limited pharmacological interventions. The present study aims to evaluate and compare …

Discovery and preclinical development of novel intraocular pressure-lowering rho kinase inhibitor: corticosteroid conjugates

J Sturdivant, SS Williams, M Ina, M Weksler… - Journal of Ocular …, 2023 - liebertpub.com
Purpose: A new class of ocular steroids designed to mitigate steroid-induced intraocular
pressure (IOP) elevation while maintaining anti-inflammatory activity was developed. Herein …