The expression of mitochondrial genes is regulated in response to the metabolic needs of
different cell types, but the basic mechanisms underlying this process are still poorly …

Mitochondria are the major source of ATP in the cell. Five multi-subunit complexes in the
inner membrane of the organelle are involved in the oxidative phosphorylation required for …

RNA G-quadruplexes (RG4s) are four-stranded structures known to control gene expression
mechanisms, from transcription to protein synthesis, and DNA-related processes. Their …

Inherited disorders of oxidative phosphorylation cause the clinically and genetically
heterogeneous diseases known as mitochondrial energy generation disorders, or …

While epigenetic modifications of DNA and histones play main roles in gene transcription
regulation, recently discovered post-transcriptional RNA modifications, known as …

Mitochondria have multiple functions, including synthesis of adenine triphosphate,
production of reactive oxygen species, calcium signalling, thermogenesis and apoptosis …

The human mitochondrial genome encodes thirteen core subunits of the oxidative
phosphorylation system, and defects in mitochondrial gene expression lead to severe …

Bisphenol A (BPA), a widely used industrial compound worldwide, was recently classified as
an environmental toxicant. The intestines and liver are responsible for detoxification in …

Mitochondria participate in a wide range of cellular processes. One essential function of
mitochondria is to be a platform for antiviral signaling proteins during the innate immune …

Mammalian mitochondrial DNA (mtDNA) is replicated and transcribed by phage-like DNA
and RNA polymerases, and our understanding of these processes has progressed …