Epidermolysis bullosa (EB) is an inherited, heterogeneous group of rare genetic dermatoses
characterized by mucocutaneous fragility and blister formation, inducible by often minimal …

The skin is one of the crucial body organs with anatomy and physiology linked to various
disorders including congenital and acquired diseases. Nowadays, mesenchymal stem cell …

Recessive dystrophic epidermolysis bullosa (RDEB) is a severe skin fragility disorder
caused by loss-of-function mutations in the COL7A1 gene, which encodes type VII collagen …

Recessive dystrophic epidermolysis bullosa (RDEB) is a severe inherited skin disorder
caused by mutations in the COL7A1 gene encoding type VII collagen (C7). The spectrum of …

Genome editing represents a promising strategy for the therapeutic correction of COL7A1
mutations that cause recessive dystrophic epidermolysis bullosa (RDEB). DNA cleavage …

Many diseases, as well as side effects of drugs, manifest themselves through skin
symptoms. Skin is a complex tissue that hosts various specialized cell types and performs …

Epidermolysis bullosa is a family of diseases characterized by blistering and fragility of the
skin in response to mechanical trauma. Advances in our understanding of epidermolysis …

Epidermolysis bullosa (EB) is the umbrella term for a group of rare inherited skin fragility
disorders caused by mutations in at least 20 different genes. There is no cure for any of the …

BACKGROUND Recessive dystrophic epidermolysis bullosa (RDEB) is a severe form of skin
fragility disorder due to mutations in COL7A1 encoding basement membrane type VII …

Recessive dystrophic epidermolysis bullosa (RDEB) is a rare monogenic blistering disorder
caused by the lack of functional type VII collagen, leading to skin fragility and subsequent …