The field of mitochondrial ion channels underwent a rapid development during the last
decade, thanks to the molecular identification of some of the nuclear-encoded organelle …

Mitochondrion, known as the “powerhouse” of the cell, regulates ion homeostasis, redox
state, cell proliferation and differentiation, and lipid synthesis. The inner mitochondrial …

Mitochondria are involved in multiple cellular tasks, such as ATP synthesis, metabolism,
metabolite and ion transport, regulation of apoptosis, inflammation, signaling, and …

Mitochondrial potassium (mitoK) channels play an important role in cellular physiology.
These channels are expressed in healthy tissues and cancer cells. Activation of mitoK …

Mitochondria play a fundamental role in the energetics of cardiac cells. Moreover,
mitochondria are involved in cardiac ischemia/reperfusion injury by opening the …

The activation of mitochondrial large conductance calcium-activated potassium (mitoBKCa)
channels increases cell survival during ischemia/reperfusion injury of cardiac cells. The …

Objectives Acute myocardial ischemia is one of the major causes of illness in western
society. Reduced coronary blood supply leads to cell death and loss of cardiomyocyte …

In this review, we describe key signaling pathways regulating potassium channels present in
the inner mitochondrial membrane. The signaling cascades covered here include …

In the 1970s, calcium-activated potassium currents were recorded for the first time. In
10years, this Ca2+-activated potassium channel was identified in rat skeletal muscle …

Hypoxia is a condition characterized by a reduction of cellular oxygen levels derived from
alterations in oxygen balance. Hypoxic events trigger changes in cell-signaling cascades …