[HTML][HTML] Ghrelin

TD Müller, R Nogueiras, ML Andermann… - Molecular …, 2015 - Elsevier
Background The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the
endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence …

[HTML][HTML] Ghrelin regulation of glucose metabolism

AL Poher, MH Tschöp, TD Müller - Peptides, 2018 - Elsevier
The a 28-amino acid peptide ghrelin was discovered in 1999 as a growth hormone (GH)
releasing peptide. Soon after its discovery, ghrelin was found to increase body weight and …

Ghrelin: structure and function

M Kojima, K Kangawa - Physiological reviews, 2005 - journals.physiology.org
Small synthetic molecules called growth hormone secretagogues (GHSs) stimulate the
release of growth hormone (GH) from the pituitary. They act through the GHS-R, a G protein …

Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin

AJ Van Der Lely, M Tschop, ML Heiman… - Endocrine …, 2004 - academic.oup.com
Ghrelin is a peptide predominantly produced by the stomach. Ghrelin displays strong GH-
releasing activity. This activity is mediated by the activation of the so-called GH …

Short-chain fatty acids and microbiota metabolites attenuate ghrelin receptor signaling

C Torres-Fuentes, AV Golubeva, AV Zhdanov… - The FASEB …, 2019 - research.rug.nl
The gastrointestinal microbiota is emerging as a unique and inexhaustible source for
metabolites with potential to modulate G-protein coupled receptors (GPCRs). The ghrelin …

Ghrelin—a hormone with multiple functions

M Korbonits, AP Goldstone, M Gueorguiev… - Frontiers in …, 2004 - Elsevier
Ghrelin is brain-gut peptide with growth hormone-releasing and appetite-inducing activities.
It is mainly secreted from the stomach mucosa but it is also expressed widely in different …

Structure and physiological actions of ghrelin

C Delporte - Scientifica, 2013 - Wiley Online Library
Ghrelin is a gastric peptide hormone, discovered as being the endogenous ligand of growth
hormone secretagogue receptor. Ghrelin is a 28 amino acid peptide presenting a unique n …

Ghrelin inhibits proinflammatory responses and nuclear factor-κB activation in human endothelial cells

WG Li, D Gavrila, X Liu, L Wang, S Gunnlaugsson… - Circulation, 2004 - Am Heart Assoc
Background—Ghrelin is a novel growth hormone-releasing peptide that has been shown to
improve cachexia in heart failure and cancer and to ameliorate the hemodynamic and …

Ghrelin, appetite, and gastric motility: the emerging role of the stomach as an endocrine organ

A Inui, A Asakawa, C Y. Bowers… - The FASEB …, 2004 - Wiley Online Library
Recent progress in the field of energy homeostasis was triggered by the discovery of
adipocyte hormone leptin and revealed a complex regulatory neuroendocrine network. A …

Ghrelin in the regulation of body weight and metabolism

TR Castaneda, J Tong, R Datta, M Culler… - Frontiers in …, 2010 - Elsevier
Ghrelin, a peptide hormone predominantly produced by the stomach, was isolated as the
endogenous ligand for the growth hormone secretagogue receptor. Ghrelin is a potent …