Vascular endothelial growth factor-A (VEGF-A) is a key mediator of angiogenesis, signalling
via the class IV tyrosine kinase receptor family of VEGF Receptors (VEGFRs). Although …

The vascular endothelial growth factor (VEGF)/vascular endothelial growth factor receptor
(VEGFR) axis is indispensable in the process of angiogenesis and has been implicated as a …

Growth factors have recently gained clinical importance for wound management. Application
of recombinant growth factors has been shown to mimic cell migration, proliferation, and …

Abstract 293 cell line (widely known as the Human Embryonic Kidney 293 cells) and its
derivatives were the most used cells after HeLa in cell biology studies and after CHO in …

Receptor tyrosine kinases (RTKs), a category of transmembrane receptors, have gained
significant clinical attention in oncology due to their central role in cancer pathogenesis …

The regulation of vascular endothelial growth factor A (VEGF) is critical to
neovascularization in numerous tissues under physiological and pathological conditions …

Acute wound healing is an orderly process of four overlapping events: haemostasis,
inflammation, proliferation and remodelling. A drug delivery system with a temporal control …

The development of the nervous and vascular systems constitutes primary events in the
evolution of the animal kingdom; the former provides electrical stimuli and coordination …

This is the second of 2 articles that discuss the biology and pathophysiology of wound
healing, reviewing the role that growth factors play in this process and describing the current …

VEGF can be secreted in multiple isoforms with variable affinity for extracellular proteins and
different abilities to induce vascular morphogenesis, but the molecular mechanisms behind …