Embracing the unknown: disentangling the complexities of the soil microbiome

N Fierer - Nature Reviews Microbiology, 2017 - nature.com
Soil microorganisms are clearly a key component of both natural and managed ecosystems.
Despite the challenges of surviving in soil, a gram of soil can contain thousands of individual …

Virus taxonomy in the age of metagenomics

P Simmonds, MJ Adams, M Benkő, M Breitbart… - Nature Reviews …, 2017 - nature.com
The number and diversity of viral sequences that are identified in metagenomic data far
exceeds that of experimentally characterized virus isolates. In a recent workshop, a panel of …

Cryptic and abundant marine viruses at the evolutionary origins of Earth's RNA virome

AA Zayed, JM Wainaina, G Dominguez-Huerta… - Science, 2022 - science.org
Whereas DNA viruses are known to be abundant, diverse, and commonly key ecosystem
players, RNA viruses are insufficiently studied outside disease settings. In this study, we …

Exploring the human microbiome: the potential future role of next-generation sequencing in disease diagnosis and treatment

MA Malla, A Dubey, A Kumar, S Yadav… - Frontiers in …, 2019 - frontiersin.org
The interaction between the human microbiome and immune system has an effect on
several human metabolic functions and impacts our well-being. Additionally, the interaction …

Ecogenomics and potential biogeochemical impacts of globally abundant ocean viruses

S Roux, JR Brum, BE Dutilh, S Sunagawa… - Nature, 2016 - nature.com
Ocean microbes drive biogeochemical cycling on a global scale. However, this cycling is
constrained by viruses that affect community composition, metabolic activity, and …

Revision of Begomovirus taxonomy based on pairwise sequence comparisons

Viruses of the genus Begomovirus (family Geminiviridae) are emergent pathogens of crops
throughout the tropical and subtropical regions of the world. By virtue of having a small DNA …

Soil viruses are underexplored players in ecosystem carbon processing

G Trubl, HB Jang, S Roux, JB Emerson, N Solonenko… - …, 2018 - Am Soc Microbiol
Rapidly thawing permafrost harbors∼ 30 to 50% of global soil carbon, and the fate of this
carbon remains unknown. Microorganisms will play a central role in its fate, and their viruses …

Global organization and proposed megataxonomy of the virus world

EV Koonin, VV Dolja, M Krupovic… - Microbiology and …, 2020 - Am Soc Microbiol
Viruses and mobile genetic elements are molecular parasites or symbionts that coevolve
with nearly all forms of cellular life. The route of virus replication and protein expression is …

The Discovery, Distribution, and Evolution of Viruses Associated with Drosophila melanogaster

CL Webster, FM Waldron, S Robertson, D Crowson… - PLoS …, 2015 - journals.plos.org
Drosophila melanogaster is a valuable invertebrate model for viral infection and antiviral
immunity, and is a focus for studies of insect-virus coevolution. Here we use a metagenomic …

Gene transfer agents: phage-like elements of genetic exchange

AS Lang, O Zhaxybayeva, JT Beatty - Nature Reviews Microbiology, 2012 - nature.com
Horizontal gene transfer is important in the evolution of bacterial and archaeal genomes. An
interesting genetic exchange process is carried out by diverse phage-like gene transfer …