Multiple endocrine neoplasia type 1 (MEN1) is a rare syndrome characterized by the co-
occurrence of primary hyperparathyroidism, duodenopancreatic neuroendocrine tumours …

Multiple endocrine neoplasia type 1 (MEN1) is a rare hereditary tumor syndrome inherited in
an autosomal dominant manner and characterized by a predisposition to a multitude of …

The better understanding of the biological behavior of multiple endocrine neoplasia type 1
(MEN1) organ manifestations and the increase in clinical experience warrant a revision of …

The androgen receptor (AR) signaling axis drives all stages of prostate cancer, including the
lethal, drug-resistant form of the disease termed castration-resistant prostate cancer (CRPC) …

Multiple endocrine neoplasia type 1 (MEN1) is a rare inherited syndrome caused by
inactivating heterozygote mutations of the MEN1 gene affecting parathyroid glands …

Primary hyperparathyroidism (PHPT), a relatively common disorder characterized by
hypercalcemia with raised or inappropriately normal serum parathyroid hormone (PTH) …

While primary hyperparathyroidism (PHPT) generally represents a common endocrine
disorder, being the more frequent cause of hypercalcemia in outpatients, familial forms of …

Cinacalcet, a positive allosteric modulator of the calcium sensing receptor (CaSR) reduces
parathyroid hormone (PTH) secretion by increasing the sensitivity of the CaSR on …

Individuals with a familial predisposition to the development of parathyroid tumors constitute
a small minority of all patients with primary hyperparathyroidism (PHPT). These familial …

Introduction Primary hyperparathyroidism is increasingly an asymptomatic disease at
diagnosis, but the recognized guidelines for management are based on evidence obtained …