Simple Summary Local breeds represent a precious reservoir of genetic diversity, crucial to
adapting to environmental and climate changes and reacting to evolving diseases. In Sicily …

Breeding programmes to promote resistance to classical scrapie, similar to those for sheep
in existing transmissible spongiform encephalopathies (TSE) regulations, have not been …

Goats are adapted to live in harsh areas of the world ensuring minimum levels of milk and
meat production without much economic input. Scrapie is a fatal prion disease of small …

Introduction Paratuberculosis (PTB) is a worldwide chronic, contagious enteric disease
caused by Mycobacterium avium subsp. paratuberculosis (MAP) mainly affecting ruminant …

Breeding towards genetic resistance to prion disease is effective in eliminating scrapie. In
sheep, classical forms of scrapie have been eradicated almost completely in several …

Aim of this study is to report a laboratory investigation performed following the isolation of
Brucella ovis, causing ovine epididymitis, in a traditional sheep farm in Sicily (South Italy) …

Background Classical scrapie susceptibility in sheep has been linked to three
polymorphisms at codon 136, 154, and 171 in the prion protein gene (PRNP) whereas …

Abstract The European Union has implemented breeding programmes to increase scrapie
resistance in sheep. A similar approach can be applied also in goats since the K222 allele …

Scrapie is a fatal, neurodegenerative disease that affects sheep and goat worldwide,
belonging to the group of transmissible spongiform encephalopathies (TSEs). Since 2002 …

Background Polymorphisms of the prion protein gene may influence scrapie susceptibility in
small ruminants through modified protein conformation. At least 47 amino acid substitutions …