Skin cancer and new treatment perspectives: A review

MCF Simoes, JJS Sousa, AACC Pais - Cancer letters, 2015 - Elsevier
Skin cancers are by far the most common malignancy of humans, particularly in the white
population. The growing incidence of cutaneous malignancies has heralded the need for …

Retinoic acid receptors: from molecular mechanisms to cancer therapy

A Di Masi, L Leboffe, E De Marinis, F Pagano… - Molecular aspects of …, 2015 - Elsevier
Retinoic acid (RA), the major bioactive metabolite of retinol or vitamin A, induces a spectrum
of pleiotropic effects in cell growth and differentiation that are relevant for embryonic …

Guidelines of care for the management of primary cutaneous melanoma

SM Swetter, H Tsao, CK Bichakjian… - Journal of the American …, 2019 - Elsevier
The incidence of primary cutaneous melanoma continues to increase each year. Melanoma
accounts for the majority of skin cancer–related deaths, but treatment is usually curative …

Completion dissection or observation for sentinel-node metastasis in melanoma

MB Faries, JF Thompson, AJ Cochran… - … England Journal of …, 2017 - Mass Medical Soc
Background Sentinel-lymph-node biopsy is associated with increased melanoma-specific
survival (ie, survival until death from melanoma) among patients with node-positive …

Safety and efficacy of vemurafenib in BRAFV600E and BRAFV600K mutation-positive melanoma (BRIM-3): extended follow-up of a phase 3, randomised, open-label …

GA McArthur, PB Chapman, C Robert, J Larkin… - The lancet …, 2014 - thelancet.com
Background In the BRIM-3 trial, vemurafenib was associated with risk reduction versus
dacarbazine of both death and progression in patients with advanced BRAF V600 mutation …

[HTML][HTML] Skin cancer epidemics in the elderly as an emerging issue in geriatric oncology

S Garcovich, G Colloca, P Sollena, B Andrea… - Aging and …, 2017 - ncbi.nlm.nih.gov
Skin cancer is a worldwide, emerging clinical need in the elderly white population, with a
steady increase in incidence rates, morbidity and related medical costs. Skin cancer is a …

Cannabidiol—From plant to human body: A promising bioactive molecule with multi-target effects in cancer

B Kis, FC Ifrim, V Buda, S Avram, IZ Pavel… - International journal of …, 2019 - mdpi.com
Cannabis sativa L. is a plant long used for its textile fibers, seed oil, and oleoresin with
medicinal and psychoactive properties. It is the main source of phytocannabinoids, with over …

Guidelines of care for the management of primary cutaneous melanoma

CK Bichakjian, AC Halpern, TM Johnson… - Journal of the American …, 2011 - Elsevier
The incidence of primary cutaneous melanoma has been increasing dramatically for several
decades. Melanoma accounts for the majority of skin cancer–related deaths, but treatment is …

Antibodies that bind PD-L1 and uses thereof

J Cogswell, SM Goldberg, AK Gupta… - US Patent …, 2015 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
48577861&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Electrochemotherapy of superficial tumors–Current status:: Basic principles, operating procedures, shared indications, and emerging applications

LG Campana, D Miklavčič, G Bertino, R Marconato… - Seminars in …, 2019 - Elsevier
Abstract Treatment of superficial tumors with electrochemotherapy (ECT) has shown a steep
rise over the past decade and indications range from skin cancers to locally advanced or …