Frailty describes an individual's vulnerability to adverse health outcomes and is a useful
construct that assists health professionals to understand the heterogeneity of the ageing …

Importance Frailty is a common geriatric syndrome of significant public health importance,
yet there is limited understanding of the risk of frailty development at a population level …

The 'male-female health-survival paradox'is a well-described clinical phenomenon. More
recently, it has been conceptualized as a 'sex-frailty paradox': females may be considered to …

Epigenetic age acceleration is considered a measure of biological aging based on genome-
wide patterns of DNA methylation. Although age acceleration has been associated with the …

Background The relationship between healthy lifestyle and frailty remains unclear. Healthy
weight is crucial for overall well-being, but using body mass index (BMI) to evaluate weight …

Objectives To assess the prevalence of frailty and identify predictors of frailty among
Chinese community-dwelling older adults with type 2 diabetes. Design A cross-sectional …

Background Frailty is an important concept for risk stratification in clinical practice, but it is
hardly acknowledged at all in mental healthcare settings. This paper aims to assess the …

Objective To examine the association of lifestyle behaviours (LSB) with physical activity (PA)
and frailty; also, to examine if associations differ by sex and age. Methods 24,828 individuals …

Alcohol drinking is a popular activity among adolescents in many countries, largely due to its
pleasant, relaxing effects. As a major concern, ethanol consumption put the drinkers at risk …

Background There is a rapid shift in the social context of drinking, with a large proportion of
regular drinkers favouring outdoor-open space drinking, such as motor-parks, by the road …