Immunosuppressive drugs in kidney transplantation: impact on patient survival, and incidence of cardiovascular disease, malignancy and infection

R Marcén - Drugs, 2009 - Springer
Renal transplant recipients have increased mortality rates when compared with the general
population. The new immunosuppressive drugs have improved short-term patient survival …

Treatment of polyomavirus infection in kidney transplant recipients: a systematic review

O Johnston, D Jaswal, JS Gill, S Doucette… - …, 2010 - journals.lww.com
Background. Polyomavirus-associated nephropathy (PVAN) is an important cause of kidney
graft loss but there is no consensus on its management. This study aimed to systematically …

[HTML][HTML] Outcomes of immunosuppression minimization and withdrawal early after liver transplantation

A Shaked, MR DesMarais, H Kopetskie, S Feng… - American Journal of …, 2019 - Elsevier
The Immune Tolerance Network ITN030ST A-WISH assessed immunosuppression
withdrawal in liver transplant recipients with hepatitis C or nonimmune nonviral liver …

[HTML][HTML] Reducing immunosuppression preserves allograft function in presumptive and definitive polyomavirus-associated nephropathy

S Schaub, HH Hirsch, M Dickenmann, J Steiger… - American Journal of …, 2010 - Elsevier
Early detection of polyomavirus BK (BKV) viremia and reduction of immunosuppression is
recommended for preventing polyomavirus-associated nephropathy (Py-VAN), but …

BK virus nephropathy and kidney transplantation

DL Bohl, DC Brennan - Clinical Journal of the American Society of …, 2007 - journals.lww.com
Nephropathy from BK virus (BKV) infection is an evolving challenge in kidney transplant
recipients. It is the consequence of modern potent immunosuppression aimed at reducing …

BK and JC virus: a review

M Pinto, S Dobson - Journal of Infection, 2014 - Elsevier
Polyomaviruses are ubiquitous, species-specific viruses belonging to the family
Papovaviridae. The two most commonly known human polyomaviruses, BK virus and JC …

[HTML][HTML] BK virus in solid organ transplant recipients

HH Hirsch, P Randhawa… - American Journal of …, 2009 - Elsevier
The human polyomavirus BK (BKV) is linked to two major complications in transplant
recipients, polyomavirus-associated nephropathy (PyVAN)(1, 2, 3, 4) and polyomavirus …

Polyomavirus BK with rearranged noncoding control region emerge in vivo in renal transplant patients and increase viral replication and cytopathology

R Gosert, CH Rinaldo, GA Funk, A Egli… - The Journal of …, 2008 - rupress.org
Immunosuppression is required for BK viremia and polyomavirus BK–associated
nephropathy (PVAN) in kidney transplants (KTs), but the role of viral determinants is unclear …

[HTML][HTML] Prospective monitoring of polyomavirus BK replication and impact of pre-emptive intervention in pediatric kidney recipients

F Ginevri, A Azzi, HH Hirsch, S Basso, I Fontana… - American Journal of …, 2007 - Elsevier
Polyoma BK virus (BKV)-associated nephropathy (PVAN) is a relevant cause of poor renal
allograft survival. In a prospective analysis, we monitored BKV DNA in blood and urine …

[HTML][HTML] BK virus nephritis after renal transplantation

S Hariharan - Kidney international, 2006 - Elsevier
BK viremia and nephritis are increasing problems in renal transplant recipients. The exact
cause of the increasing prevalence of this condition remains poorly understood. Increasing …