Stroke constitutes the second leading cause of death and a major cause of disability
worldwide. Stroke is normally classified as either ischemic or hemorrhagic stroke (HS) …

Cancer is the second biggest cause of death worldwide. Despite a number of studies being
conducted, the effective mechanism for treating cancer has not yet been fully understood …

The intracellular calcium ions (Ca 2+) act as second messenger to regulate gene
transcription, cell proliferation, migration and death. Accumulating evidences have …

Terpenoids are the largest class of natural products, most of which are derived from plants.
Amongst their numerous biological properties, their anti-tumor effects are of interest for they …

Abstract Macroautophagy (hereafter called 'autophagy') is a cellular process for degrading
and recycling cellular constituents, and for maintenance of cell function. Autophagy initiates …

Introduction: Terpenoids constitute the largest class of natural products and are a rich
reservoir of candidate compounds for drug discovery. Recent efforts into the research and …

Autophagy is a cellular process responsible for delivery of proteins or organelles to
lysosomes. It participates not only in maintaining cellular homeostasis, but also in promoting …

Abstract Sirtuin 1 (SIRT1) has been implicated in telomere maintenance and the growth of
hepatocellular carcinoma (HCC). Nevertheless, the role of other sirtuins in the pathogenesis …

Accumulated evidence indicates that autophagy is a response of cancer cells to various anti-
cancer therapies. Autophagy is designated as programmed cell death type II, and is …

Autophagy is an important cellular process that controls cells in a normal homeostatic state
by recycling nutrients to maintain cellular energy levels for cell survival via the turnover of …