Mechanisms of vascular aging
Aging of the vasculature plays a central role in morbidity and mortality of older people. To
develop novel treatments for amelioration of unsuccessful vascular aging and prevention of …
develop novel treatments for amelioration of unsuccessful vascular aging and prevention of …
Genetics of thoracic and abdominal aortic diseases: aneurysms, dissections, and ruptures
Dissections or ruptures of aortic aneurysms remain a leading cause of death in the
developed world, with the majority of deaths being preventable if individuals at risk are …
developed world, with the majority of deaths being preventable if individuals at risk are …
[HTML][HTML] The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm
Background Decision-making related to the care of patients with an abdominal aortic
aneurysm (AAA) is complex. Aneurysms present with varying risks of rupture, and patient …
aneurysm (AAA) is complex. Aneurysms present with varying risks of rupture, and patient …
Mechanisms of Vascular Aging, A Geroscience Perspective: JACC Focus Seminar
Age-related pathological alterations of the vasculature have a critical role in morbidity and
mortality of older adults. In epidemiological studies, age is the single most important …
mortality of older adults. In epidemiological studies, age is the single most important …
Understanding the pathogenesis of abdominal aortic aneurysms
An aortic aneurysm is a dilatation in which the aortic diameter is≥ 3.0 cm. If left untreated,
the aortic wall continues to weaken and becomes unable to withstand the forces of the …
the aortic wall continues to weaken and becomes unable to withstand the forces of the …
[HTML][HTML] Risk factors for abdominal aortic aneurysm in population-based studies: a systematic review and meta-analysis
E Altobelli, L Rapacchietta, VF Profeta… - International journal of …, 2018 - mdpi.com
Abdominal aortic aneurysm (AAA) represents an important public health problem with a
prevalence between 1.3% and 12.5%. Several population-based randomized trials have …
prevalence between 1.3% and 12.5%. Several population-based randomized trials have …
Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms
FM Davis, LC Tsoi, WJ Melvin, A DenDekker… - Journal of Experimental …, 2021 - rupress.org
Abdominal aortic aneurysms (AAAs) are a life-threatening disease for which there is a lack
of effective therapy preventing aortic rupture. During AAA formation, pathological vascular …
of effective therapy preventing aortic rupture. During AAA formation, pathological vascular …
[HTML][HTML] The care of patients with an abdominal aortic aneurysm: the Society for Vascular Surgery practice guidelines
EL Chaikof, DC Brewster, RL Dalman… - Journal of vascular …, 2009 - jvascsurg.org
The Clinical Practice Council of the Society for Vascular Surgery charged a writing
committee with the task of updating practice guidelines, initally published in 2003, for …
committee with the task of updating practice guidelines, initally published in 2003, for …
[HTML][HTML] Genetic and epigenetic mechanisms underlying vascular smooth muscle cell phenotypic modulation in abdominal aortic aneurysm
R Gurung, AM Choong, CC Woo, R Foo… - International journal of …, 2020 - mdpi.com
Abdominal aortic aneurysm (AAA) refers to the localized dilatation of the infra-renal aorta, in
which the diameter exceeds 3.0 cm. Loss of vascular smooth muscle cells, degradation of …
which the diameter exceeds 3.0 cm. Loss of vascular smooth muscle cells, degradation of …
[HTML][HTML] Abdominal aortic aneurysm formation with a focus on vascular smooth muscle cells
Abdominal aortic aneurysm (AAA) is a lethal degenerative vascular disease that affects,
mostly, the elder population, with a high mortality rate (> 80%) upon rupture. It features a …
mostly, the elder population, with a high mortality rate (> 80%) upon rupture. It features a …