A new definition of poststroke spasticity and the interference of spasticity with motor recovery from acute to chronic stages
The relationship of poststroke spasticity and motor recovery can be confusing.“True” motor
recovery refers to return of motor behaviors to prestroke state with the same end-effectors …
recovery refers to return of motor behaviors to prestroke state with the same end-effectors …
Brainstem circuits controlling action diversification
L Ruder, S Arber - Annual review of neuroscience, 2019 - annualreviews.org
Neuronal circuits that regulate movement are distributed throughout the nervous system.
The brainstem is an important interface between upper motor centers involved in action …
The brainstem is an important interface between upper motor centers involved in action …
A unifying pathophysiological account for post-stroke spasticity and disordered motor control
Cortical and subcortical plastic reorganization occurs in the course of motor recovery after
stroke. It is largely accepted that plasticity of ipsilesional motor cortex primarily contributes to …
stroke. It is largely accepted that plasticity of ipsilesional motor cortex primarily contributes to …
Extensive cortical convergence to primate reticulospinal pathways
Early evolution of the motor cortex included development of connections to brainstem
reticulospinal neurons; these projections persist in primates. In this study, we examined the …
reticulospinal neurons; these projections persist in primates. In this study, we examined the …
Premotor cortical-cerebellar reorganization in a macaque model of primary motor cortical lesion and recovery
Neuromotor systems have the capacity for functional recovery following local damage. The
literature suggests a possible role for the premotor cortex and cerebellum in motor recovery …
literature suggests a possible role for the premotor cortex and cerebellum in motor recovery …
Recovery after spinal cord injury is enhanced by anti-Nogo-A antibody therapy—from animal models to clinical trials
AM Sartori, AS Hofer, ME Schwab - Current Opinion in Physiology, 2020 - Elsevier
The ability of the central nervous system to regenerate over long distances after a lesion is
restricted by the presence of physical and biochemical barriers, neuronal growth programs …
restricted by the presence of physical and biochemical barriers, neuronal growth programs …
Loss of motor cortical inputs to the red nucleus after CNS disorders in nonhuman primates
S Borgognon, EM Rouiller - Journal of Neuroscience, 2023 - Soc Neuroscience
The premotor (PM) and primary motor (M1) cortical areas broadcast voluntary motor
commands through multiple neuronal pathways, including the corticorubral projection that …
commands through multiple neuronal pathways, including the corticorubral projection that …
The unsolved role of heightened connectivity from the unaffected hemisphere to paretic arm muscles in chronic stroke
U Hammerbeck, D Hoad, R Greenwood… - Clinical …, 2019 - Elsevier
Objective Ipsilateral connectivity from the non-stroke hemisphere to paretic arm muscles
appears to play little role in functional recovery, which instead depends on contralateral …
appears to play little role in functional recovery, which instead depends on contralateral …
Functional near-infrared-spectroscopy-based measurement of changes in cortical activity in macaques during post-infarct recovery of manual dexterity
Because compensatory changes in brain activity underlie functional recovery after brain
damage, monitoring of these changes will help to improve rehabilitation effectiveness …
damage, monitoring of these changes will help to improve rehabilitation effectiveness …
Cortical projection from the premotor or primary motor cortex to the subthalamic nucleus in intact and parkinsonian adult macaque monkeys: a pilot tracing study
S Borgognon, J Cottet, S Badoud, J Bloch… - Frontiers in neural …, 2020 - frontiersin.org
Besides the main cortical inputs to the basal ganglia, via the corticostriatal projection, there
is another input via the corticosubthalamic projection (CSTP), terminating in the subthalamic …
is another input via the corticosubthalamic projection (CSTP), terminating in the subthalamic …