Applications of vibrational spectroscopy for analysis of connective tissues
Advances in vibrational spectroscopy have propelled new insights into the molecular
composition and structure of biological tissues. In this review, we discuss common …
composition and structure of biological tissues. In this review, we discuss common …
Reproducing the biomechanical environment of the chondrocyte for cartilage tissue engineering
P Statham, E Jones, LM Jennings… - Tissue Engineering Part …, 2022 - liebertpub.com
It is well known that the biomechanical and tribological performance of articular cartilage is
inextricably linked to its extracellular matrix (ECM) structure and zonal heterogeneity …
inextricably linked to its extracellular matrix (ECM) structure and zonal heterogeneity …
Sensor technologies for quality control in engineered tissue manufacturing
The use of engineered cells, tissues, and organs has the opportunity to change the way
injuries and diseases are treated. Commercialization of these groundbreaking technologies …
injuries and diseases are treated. Commercialization of these groundbreaking technologies …
Structural origins of cartilage shear mechanics
Articular cartilage is a remarkable material able to sustain millions of loading cycles over
decades of use outperforming any synthetic substitute. Crucially, how extracellular matrix …
decades of use outperforming any synthetic substitute. Crucially, how extracellular matrix …
The mechanics of embedded fiber networks
Fiber networks underlie the mechanical behavior of a wide range of natural and engineered
materials. Interestingly, these networks are often embedded within amorphous matrices …
materials. Interestingly, these networks are often embedded within amorphous matrices …
Instabilities induced by mechanical loading determine the viability of chondrocytes grown on porous scaffolds
Tissue-engineered cartilage constructs have shown promise to treat focal cartilage defects
in multiple clinical studies. Notably, products in clinical use or in late-stage clinical trials …
in multiple clinical studies. Notably, products in clinical use or in late-stage clinical trials …
Microscale strain mapping demonstrates the importance of interface slope in the mechanics of cartilage repair
Achieving lateral integration of articular cartilage repair tissue with surrounding native
cartilage remains a clinical challenge. Histological and bulk mechanical studies have …
cartilage remains a clinical challenge. Histological and bulk mechanical studies have …
Microscale strain concentrations in tissue-engineered osteochondral implants are dictated by local compositional thresholds and architecture
B Kim, TAN Kelly, HJ Jung, OS Beane… - Journal of …, 2024 - Elsevier
Tissue-engineered osteochondral implants manufactured from condensed mesenchymal
stem cell bodies have shown promise for treating focal cartilage defects. Notably, such …
stem cell bodies have shown promise for treating focal cartilage defects. Notably, such …
[PDF][PDF] Relationship between microscale shear modulus, composition, and structure in porcine, canine, and human temporomandibular-joint cartilage: relevance to …
Fully understanding the complex mechanical function of temporomandibular joint (TMJ)
cartilage and the compositional and structural organization that underlie it is a persistent …
cartilage and the compositional and structural organization that underlie it is a persistent …
The Role of Buckling Instabilities in the Global and Local Mechanical Response in Porous Collagen Scaffolds
Background Porous polymer scaffolds are commonly used for regenerative medicine and
tissue-engineered therapies in the repair and regeneration of structural tissues which …
tissue-engineered therapies in the repair and regeneration of structural tissues which …