A growing need exists for reliable in-vivo measurement of neuroinflammation to better
characterise the inflammatory processes underlying various diseases and to inform the …

Neuroinflammation play an important role in Alzheimer's disease pathogenesis. Advances in
molecular imaging using positron emission tomography have provided insights into the time …

Compelling experimental evidence suggests that microglial activation is involved in the
spread of tau tangles over the neocortex in Alzheimer's disease (AD). We tested the …

Brain network dysfunction is increasingly recognised in Alzheimer's disease (AD). However,
the causes of brain connectivity disruption are still poorly understood. Recently …

Animal studies suggest that the apolipoprotein E ε4 (APOE ε4) allele is a culprit of early
microglial activation in Alzheimer's disease (AD). Here, we tested the association between …

Alzheimer's disease (AD) is a neurodegenerative disorder that usually develops slowly and
progressively worsens over time. Although there has been increasing research interest in …

Tau pathology, neuroinflammation, and neurodegeneration are key aspects of Alzheimer's
disease. Understanding whether these features predict cognitive decline, alone or in …

The past decade has seen the convergence of a series of new insights that arose from
genetic and systems analyses of Alzheimer's disease (AD) with a wealth of epidemiological …

Neuroinflammation plays a major role in the etiopathology of neurodegenerative diseases,
including Alzheimer and Parkinson diseases, frontotemporal lobar degeneration, and …

Neuroinflammation is a significant contributor to Alzheimer's disease (AD). Until now, PET
imaging of the translocator protein (TSPO) has been widely used to depict the neuroimmune …