The leukotrienes and lipoxins are biologically active metabolites derived from arachidonic
acid. Their diverse and potent actions are associated with specific receptors. Recent …

Leukotrienes (LT) are a class of inflammatory mediators produced by the 5-lipoxygenase (5-
LO) enzyme from arachidonic acid (AA). We discussed the various LT inhibitors and …

Nitric oxide in exhaled air (Feno) is increased in asthmatic children, probably reflecting
aspects of airway inflammation. We have studied the effect of the leukotriene receptor …

The possible role of leukotriene D4 (LTD4) in nasal allergy was investigated in healthy
volunteers. Nasal blood flow, nasal airway resistance, nasal discharge and nasal itching …

Cysteinyl leukotrienes (Cys-LTs) are mediators released in asthma and virus-induced
wheezing. Corticosteroids appear to have little or no effect on this release in vivo. Cys-LTs …

Cysteinyl leukotrienes, synthesized de novo from cell membrane phospholipids, are
proinflammatory mediators that play an important role in the pathophysiology of asthma …

Simple Summary Vectors are organisms that can transmit infectious pathogens from a host
(human or animal) to another. Many vectors (including mosquitoes, sand flies and ticks) …

The highly expressed D7 protein family of mosquito saliva has previously been shown to act
as an anti-inflammatory mediator by binding host biogenic amines and cysteinyl …

Conclusions In conclusion the leukotrienes appear to fulfill the major criteria as mediators of
inflammation. They have been shown to be present at a variety of inflammatory sites and to …

Inflammation is an essential component of asthma pathophysiology. While β2‐agonists are
often used for short‐term relief of acute bronchospasm, anti‐inflammatory agents are …