Objective: To review recent advances in understanding the role of leptin in the physiology
and pathophysiology of reproduction, with a focus on relevant clinical situations. Design: A …

OBJECTIVE: To summarize the effects of novel hormones (leptin, ghrelin, adiponectin,
resistin, and PYY3-36) secreted from adipose tissue and the gastrointestinal tract that have …

Leptin, a hormonal product of the Lep gene, is expressed by adipocytes and is thought to
play a role in regulating food intake and reproduction. The leptin protein has been localized …

The relationship of leptin to thyroid and sex hormones, insulin, energy intake, exercise
energy expenditure, and reproductive function was assessed in 39 female athletes. They …

Leptin is a 16-kDa cytokine secreted in humans primarily but not exclusively by adipose
tissues. Its concentration in blood is usually proportional to body fat mass, but is higher in …

Leptin, the product of the ob gene, is a small peptide molecule synthesized by white
adipocytes with an important role in the regulation of body fat and food intake. Leptin and …

Leptin is an adipocyte-derived hormone which plays a central role in the regulation of body
weight and energy homeostasis and in signalling to the brain that adequate energy stores …

Leptin participates in regulation of ovarian folliculogenesis indirectly via control of luteinizing
hormone and follicle-stimulating hormone secretion. More recent evidence suggests that …

Recently, adipose tissue has been identified as endocrine organ in addition to its action as
energy store; it produces a large number of biologically active mediators known as …

The satiety factor leptin is expressed in several reproductive tissues, but its role in the control
of reproductive physiology is not well understood. We studied leptin concentrations in the …