There have been extensive developments on cellular and molecular mechanisms of
immune regulation in allergy, asthma, autoimmune diseases, tumor development, organ …

Cytokines and chemokines are secreted proteins involved in numerous aspects of cell
growth, differentiation, and activation. A prominent feature of these molecules is their effect …

Colonic antigen-experienced lymphocytes such as tissue-resident memory CD8+ T cells can
respond rapidly to repeated antigen exposure. However, their cellular phenotypes and the …

Abstract Interleukin (IL)-26 is a TH17 cytokine with known antimicrobial and pro-
inflammatory functions. However, the precise role of IL-26 in the context of pathogenic TH17 …

Advancing our understanding of mechanisms of immune regulation in allergy, asthma,
autoimmune diseases, tumor development, organ transplantation, and chronic infections …

Natural killer (NK) cells are classically viewed as lymphocytes that provide innate
surveillance against virally infected cells and tumour cells through the release of cytolytic …

TH-17 cells are a distinct lineage of proinflammatory T helper cells that are essential for
autoimmune disease. In mice, commitment to the TH-17 lineage is dependent on …

Abstract TH-17 cells are interleukin 17 (IL-17)–secreting CD4+ T helper cells involved in
autoimmune disease and mucosal immunity. In naive CD4+ T cells from mice, IL-17 is …

Chronic liver injury with any etiology can progress to fibrosis and the end-stage diseases
cirrhosis and hepatocellular carcinoma. The progression of liver disease is controlled by a …

Cytokines play a very important role in nearly all aspects of inflammation and immunity. The
term'interleukin'(IL) has been used to describe a group of cytokines with complex …