Fertility preservation: how to preserve ovarian function in children, adolescents and adults

MM Dolmans, C Hossay, TYT Nguyen… - Journal of clinical …, 2021 - mdpi.com
Chemotherapy, pelvic radiotherapy and ovarian surgery have known gonadotoxic effects
that can lead to endocrine dysfunction, cessation of ovarian endocrine activity and early …

Factors influencing the in vitro maturation (IVM) of human oocyte

H Yang, T Kolben, S Meister, C Paul, J van Dorp… - Biomedicines, 2021 - mdpi.com
In vitro maturation (IVM) of oocytes is a promising assisted reproductive technology (ART)
deemed as a simple and safe procedure. It is mainly used in patients with impaired oocyte …

FGF2, LIF, and IGF1 (FLI) supplementation during human in vitro maturation enhances markers of gamete competence

F Amargant, LT Zhou, Y Yuan, A Nahar… - Human …, 2023 - academic.oup.com
STUDY QUESTION Does a chemically defined maturation medium supplemented with
FGF2, LIF, and IGF1 (FLI) improve in vitro maturation (IVM) of cumulus–oocyte complexes …

Present state and future outlook for the application of in vitro oocyte maturation in human infertility treatment

RL Krisher - Biology of Reproduction, 2022 - academic.oup.com
In vitro oocyte maturation is an assisted reproductive technology in which a meiotically
immature oocyte (prophase I or germinal vesicle stage) is recovered from an antral follicle …

Pre-pubertal oocytes harbor altered histone modifications and chromatin configuration

P Wasserzug Pash, G Karavani, E Reich… - Frontiers in Cell and …, 2023 - frontiersin.org
Pre-pubertal oocytes are still dormant. They are arrested in a GV state and do not undergo
meiotic divisions naturally. A multitude of molecular pathways are changed and triggered …

Prior exposure to chemotherapy does not reduce the in vitro maturation potential of oocytes obtained from ovarian cortex in cancer patients

G Karavani, K Vedder, E Gutman-Ido… - Human …, 2023 - academic.oup.com
STUDY QUESTION Does chemotherapy exposure affect IVM potential of immature oocytes
retrieved from the ovarian cortex following ovarian tissue cryopreservation (OTC) for fertility …

Rescue in vitro maturation may increase the pregnancy outcomes among women undergoing intracytoplasmic sperm injection

DY Qin, HH Jiang, QY Yao, W Yao, XQ Yuan… - Frontiers in …, 2022 - frontiersin.org
Introduction To investigate whether rescue in vitro maturation (R-IVM) improves the
reproductive outcomes among women undergoing intracytoplasmic sperm injection (ICSI) …

In vitro maturation of oocytes for fertility preservation: a comprehensive review

M Grynberg, N Sermondade, I Sellami, A Benoit… - F&S Reviews, 2022 - Elsevier
The development of oncofertility over the past decade has renewed the interest in in vitro
maturation (IVM) because of the specificity of some oncologic situations that may prevent the …

A Federated Blockchain Approach for Fertility Preservation and Assisted Reproduction in Smart Cities

DY Liao - Smart Cities, 2022 - mdpi.com
Modern life is making people infertile. Giving birth later in life is wreaking havoc on our
fertility and threatening human survival. Smart cities intend to optimize the quality of life of …

Expert consensus on fertility preservation in hematopoietic stem cell transplantation in girls in China

X Ruan - Gynecological Endocrinology, 2023 - Taylor & Francis
Aims: Preconditioning before hematopoietic stem cell transplantation (HSCT) seriously
damages the ovarian function and causes female infertility. This consensus focuses on the …