Anthelmintic drugs for treating ascariasis

LO Conterno, MD Turchi, I Corrêa… - Cochrane Database …, 2020 - cochranelibrary.com
Background Ascaris lumbricoides is a common infection, and mainly affects children living in
low‐income areas. Water and sanitation improvement, health education, and drug treatment …

Thiazolidin-4-one-based derivatives–Efficient tools for designing antiprotozoal agents. A review of the last decade

H Tuszewska, J Szczepański, S Mandziuk… - Bioorganic Chemistry, 2023 - Elsevier
Thiazolidin-4-one derivatives have a wide range of therapeutic implementations and clinical
significance for medicinal chemistry. This heterocyclic ring has been reported to possess a …

From Bench to Bedside: What Do We Know about Imidazothiazole Derivatives So Far?

M Guo, X Yu, YZ Zhu, Y Yu - Molecules, 2023 - mdpi.com
Imidazothiazole derivatives are becoming increasingly important in therapeutic use due to
their outstanding physiological activities. Recently, applying imidazothiazole as the core …

Levamisole enhances DR4-independent apoptosis induced by TRAIL through inhibiting the activation of JNK in lung cancer

X Qiao, C Wang, W Wang, Y Shang, Y Li, J Ni, S Chen - Life Sciences, 2020 - Elsevier
The headings aims Levamisole has anti-parasite and antitumor activities, but the anti-lung
cancer mechanism has not been studied. Tumor necrosis factor-related apoptosis-inducing …

An update on the current and emerging pharmacotherapy for the treatment of human ascariasis

KL Hon, AKC Leung - Expert Opinion on Pharmacotherapy, 2024 - Taylor & Francis
ABSTRACT Introduction Globally, Ascaris lumbricoides is the commonest helminthic
infection that affects people in underdeveloped countries and returning immigrants in …

Present drugs and future perspectives in treating soil-transmitted helminthiasis

J Keiser - Frontiers in Tropical Diseases, 2023 - frontiersin.org
Soil-transmitted helminthiases caused by Ascaris lumbricoides, Trichuris trichiura, and
hookworm (Ancylostoma duodenale and Necator americanus) are responsible for the …

Higher efficacy of a single dosage albendazole and different soil-transmitted helminths re-infection profiles amongst indigenous Negritos from inland jungle versus …

A Muslim, YAL Lim - Tropical Biomedicine, 2022 - europepmc.org
Demarginalization through initiation of resettlement program since 1978 is an inevitable
progress faced by the indigenous Orang Asli (OA) population in Peninsular Malaysia. As …

Scaffolds imparting anthelmintic activity: recent advancements and SAR studies

P Kumar, R Bhatia, NK Rangra - Molecular Diversity, 2024 - Springer
Helminthiasis, affecting billions globally, poses a significant health concern, especially in
impoverished regions with inadequate sanitation. The intricate anatomical complexity of …

Zirconium oxide nanoparticles modified carbon paste electrode for simultaneous voltammetric determination of mebendazole and levamisole hydrochloride in …

RT El‐Eryan, SS Toubar, AA Ashour… - …, 2022 - Wiley Online Library
A new, simple and highly sensitive electrochemical method based on zirconium oxide
nanoparticles modified carbon paste electrode (2% ZrO2/CPE) was used for simultaneous …

Immunomodulatory effects of albendazole, trichlorobendazole and wortmannilactone F on Clonorchis sinensis infection

G Duan, B Zhang, X Gong, L Xun, X Zhao, Y Li, Z Song - 2024 - researchsquare.com
Background Albendazole, trichlorobendazole and wortmannilactone F are widely used anti-
trematode drugs to treat fluke worm infections. However, their immunomodulatory effects …