Involvement of neural transient receptor potential channels in peripheral inflammation
HA Silverman, A Chen, NL Kravatz… - Frontiers in …, 2020 - frontiersin.org
Transient receptor potential (TRP) channels are a superfamily of non-selective cation
channels that act as polymodal sensors in many tissues throughout mammalian organisms …
channels that act as polymodal sensors in many tissues throughout mammalian organisms …
TRPV4—a missing link between mechanosensation and immunity
L Michalick, WM Kuebler - Frontiers in immunology, 2020 - frontiersin.org
Transient receptor potential vanilloid-type 4 (TRPV4) cation channel is widely expressed in
all tissues as well as in immune cells and its function as mechanosensitive Ca2+ channel …
all tissues as well as in immune cells and its function as mechanosensitive Ca2+ channel …
The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4+ T cells
S Bertin, Y Aoki-Nonaka, PR De Jong, LL Nohara… - Nature …, 2014 - nature.com
Abstract TRPV1 is a Ca2+-permeable channel studied mostly as a pain receptor in sensory
neurons. However, its role in other cell types is poorly understood. Here we found that …
neurons. However, its role in other cell types is poorly understood. Here we found that …
[HTML][HTML] Distribution and expression of non-neuronal transient receptor potential (TRPV) ion channels in rosacea
M Sulk, S Seeliger, J Aubert, VD Schwab… - Journal of investigative …, 2012 - Elsevier
Rosacea is a frequent chronic inflammatory skin disease of unknown etiology. Because
early rosacea reveals all characteristics of neurogenic inflammation, a central role of …
early rosacea reveals all characteristics of neurogenic inflammation, a central role of …
New insights on the role of TRP channels in calcium signalling and immunomodulation: review of pathways and implications for clinical practice
Calcium is the most abundant mineral in the human body and is central to many
physiological processes, including immune system activation and maintenance. Studies …
physiological processes, including immune system activation and maintenance. Studies …
Role of transient receptor potential vanilloid 4 in neutrophil activation and acute lung injury
J Yin, L Michalick, C Tang, A Tabuchi… - American journal of …, 2016 - atsjournals.org
The cation channel transient receptor potential vanilloid (TRPV) 4 is expressed in
endothelial and immune cells; however, its role in acute lung injury (ALI) is unclear. The …
endothelial and immune cells; however, its role in acute lung injury (ALI) is unclear. The …
Cannabidiol causes endothelium-dependent vasorelaxation of human mesenteric arteries via CB1 activation
Aims The protective effects of cannabidiol (CBD) have been widely shown in preclinical
models and have translated into medicines for the treatment of multiple sclerosis and …
models and have translated into medicines for the treatment of multiple sclerosis and …
Endocannabinoids modulate human blood–brain barrier permeability in vitro
WH Hind, C Tufarelli, M Neophytou… - British journal of …, 2015 - Wiley Online Library
Background and Purpose Endocannabinoids alter permeability at various epithelial barriers,
and cannabinoid receptors and endocannabinoid levels are elevated by stroke, with …
and cannabinoid receptors and endocannabinoid levels are elevated by stroke, with …
A molecular signature in blood identifies early Parkinson's disease
L Molochnikov, JM Rabey, E Dobronevsky… - Molecular …, 2012 - Springer
Background The search for biomarkers in Parkinson's disease (PD) is crucial to identify the
disease early and monitor the effectiveness of neuroprotective therapies. We aim to assess …
disease early and monitor the effectiveness of neuroprotective therapies. We aim to assess …
Oxidative stress mediates thalidomide-induced pain by targeting peripheral TRPA1 and central TRPV4
F De Logu, G Trevisan, IM Marone, E Coppi… - BMC biology, 2020 - Springer
Background The mechanism underlying the pain symptoms associated with
chemotherapeutic-induced peripheral neuropathy (CIPN) is poorly understood. Transient …
chemotherapeutic-induced peripheral neuropathy (CIPN) is poorly understood. Transient …