MicroRNAs in development and disease

D Sayed, M Abdellatif - Physiological reviews, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

[HTML][HTML] MicroRNAs and the cell cycle

MJ Bueno, M Malumbres - Biochimica et Biophysica Acta (BBA)-Molecular …, 2011 - Elsevier
The control of cell proliferation by microRNAs (miRNAs) is well established and the
alteration of these small, non-coding RNAs may contribute to tumor development by …

[HTML][HTML] MiR-146a inhibits oxidized low-density lipoprotein-induced lipid accumulation and inflammatory response via targeting toll-like receptor 4

K Yang, YS He, XQ Wang, L Lu, QJ Chen, J Liu, Z Sun… - FEBS letters, 2011 - Elsevier
Atherosclerosis is an inflammatory process due to oxidized low-density lipoprotein (oxLDL)
accumulation in macrophages. We investigated the involvement of microRNAs in oxLDL …

Anti-cancer effects of green tea polyphenols against prostate cancer

Y Miyata, Y Shida, T Hakariya, H Sakai - Molecules, 2019 - mdpi.com
Prostate cancer is the most common cancer among men. Green tea consumption is reported
to play an important role in the prevention of carcinogenesis in many types of malignancies …

The role of non-coding RNAs in controlling cell cycle related proteins in cancer cells

S Ghafouri-Fard, H Shoorei, FT Anamag… - Frontiers in …, 2020 - frontiersin.org
Cell cycle is regulated by a number of proteins namely cyclin-dependent kinases (CDKs)
and their associated cyclins which bind with and activate CDKs in a phase specific manner …

MicroRNAs in prostate cancer: Functional role as biomarkers

R Kanwal, AR Plaga, X Liu, GC Shukla, S Gupta - Cancer Letters, 2017 - Elsevier
MicroRNAs (miRNAs) are small endogenous non-coding molecules that alters gene
expression through post-transcriptional regulation of messenger RNA. Compelling evidence …

Myocardial AKT: the omnipresent nexus

MA Sussman, M Völkers, K Fischer… - Physiological …, 2011 - journals.physiology.org
One of the greatest examples of integrated signal transduction is revealed by examination of
effects mediated by AKT kinase in myocardial biology. Positioned at the intersection of …

MicroRNA-320 suppresses the stem cell-like characteristics of prostate cancer cells by downregulating the Wnt/beta-catenin signaling pathway

IS Hsieh, KC Chang, YT Tsai, JY Ke, PJ Lu… - …, 2013 - academic.oup.com
Prostate cancer (PCa) is a leading cause of mortality and morbidity in men worldwide, and
emerging evidence suggests that the CD44 high prostate tumor-initiating cells (TICs) are …

[HTML][HTML] Green tea polyphenol EGCG blunts androgen receptor function in prostate cancer

IA Siddiqui, M Asim, BB Hafeez, VM Adhami… - The FASEB …, 2011 - ncbi.nlm.nih.gov
Androgen deprivation therapy is the major treatment for advanced prostate cancer (PCa).
However, it is a temporary remission, and the patients almost inevitably develop hormone …

MicroRNA-101 is down-regulated in gastric cancer and involved in cell migration and invasion

HJ Wang, HJ Ruan, XJ He, YY Ma, XT Jiang… - European journal of …, 2010 - Elsevier
MicroRNAs (miRNAs) are short non-coding RNA molecules playing regulatory roles by
repressing translation or cleaving RNA transcripts. Dysregulated expression of miRNAs is …