[HTML][HTML] Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targets
M Farahani, Z Niknam, LM Amirabad… - Biomedicine & …, 2022 - Elsevier
Deciphering the molecular downstream consequences of severe acute respiratory
syndrome coronavirus (SARS-CoV)− 2 infection is important for a greater understanding of …
syndrome coronavirus (SARS-CoV)− 2 infection is important for a greater understanding of …
Host factors in coronavirus replication
AH De Wilde, EJ Snijder, M Kikkert… - Roles of host gene and …, 2018 - Springer
Coronaviruses are pathogens with a serious impact on human and animal health. They
mostly cause enteric or respiratory disease, which can be severe and life threatening, eg, in …
mostly cause enteric or respiratory disease, which can be severe and life threatening, eg, in …
[HTML][HTML] SARS-CoV-2 disrupts splicing, translation, and protein trafficking to suppress host defenses
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently identified
coronavirus that causes the respiratory disease known as coronavirus disease 2019 (COVID …
coronavirus that causes the respiratory disease known as coronavirus disease 2019 (COVID …
A scoping review of the pathophysiology of COVID-19
COVID-19 is a highly heterogeneous and complex medical disorder; indeed, severe COVID-
19 is probably amongst the most complex of medical conditions known to medical science …
19 is probably amongst the most complex of medical conditions known to medical science …
Improving mRNA-based therapeutic gene delivery by expression-augmenting 3′ UTRs identified by cellular library screening
AGO von Niessen, MA Poleganov, C Rechner… - Molecular Therapy, 2019 - cell.com
Synthetic mRNA has emerged as a powerful tool for the transfer of genetic information, and it
is being explored for a variety of therapeutic applications. Many of these applications require …
is being explored for a variety of therapeutic applications. Many of these applications require …
Immune responses and immunoprotection in crustaceans with special reference to shrimp
A Kulkarni, S Krishnan, D Anand… - Reviews in …, 2021 - Wiley Online Library
Crustacean aquaculture, dominated by shrimp, is a highly profitable food‐producing sector
in the world. However, a variety of biotic and abiotic stressors can have adverse effect on the …
in the world. However, a variety of biotic and abiotic stressors can have adverse effect on the …
A diverse range of gene products are effectors of the type I interferon antiviral response
JW Schoggins, SJ Wilson, M Panis, MY Murphy… - Nature, 2011 - nature.com
The type I interferon response protects cells against invading viral pathogens. The cellular
factors that mediate this defence are the products of interferon-stimulated genes (ISGs) …
factors that mediate this defence are the products of interferon-stimulated genes (ISGs) …
Pathogen recognition by the innate immune system
Microbial infection initiates complex interactions between the pathogen and the host.
Pathogens express several signature molecules, known as pathogen-associated molecular …
Pathogens express several signature molecules, known as pathogen-associated molecular …
Pattern recognition receptors and central nervous system repair
Pattern recognition receptors (PRRs) are part of the innate immune response and were
originally discovered for their role in recognizing pathogens by ligating specific pathogen …
originally discovered for their role in recognizing pathogens by ligating specific pathogen …
Developing mRNA-vaccine technologies
T Schlake, A Thess, M Fotin-Mleczek, KJ Kallen - RNA biology, 2012 - Taylor & Francis
mRNA vaccines combine desirable immunological properties with an outstanding safety
profile and the unmet flexibility of genetic vaccines. Based on in situ protein expression …
profile and the unmet flexibility of genetic vaccines. Based on in situ protein expression …