The success of cancer immunotherapy relies on the knowledge of the tumor
microenvironment and the immune evasion mechanisms in which the tumor, stroma, and …

Eosinophils play a homeostatic role in the body's immune responses. These cells are
involved in combating some parasitic, bacterial, and viral infections and certain cancers and …

Immune checkpoint blockade (ICB) has heralded a new era in cancer therapy. Research
into the mechanisms underlying response to ICB has predominantly focused on T cells; …

Eosinophils are evolutionarily conserved, pleotropic cells that display key effector functions
in allergic diseases, such as asthma. Nonetheless, eosinophils infiltrate multiple tumours …

Eosinophils are important effector cells and therapeutic targets in allergic diseases.
Emerging data indicate that eosinophils infiltrate a variety of solid tumor types and have …

Group 2 innate lymphoid cells (ILC2s) are essential to maintain tissue homeostasis. In
cancer, ILC2s can harbor both pro-tumorigenic and anti-tumorigenic functions, but we know …

Background Despite treatment advancements with immunotherapy, our understanding of
response relies on tissue-based, static tumor features such as tumor mutation burden (TMB) …

The enigmatic eosinophil has emerged as an exciting component of the immune system,
involved in a plethora of homeostatic and inflammatory responses. Substantial progress has …

Despite being an integral part of the immune response in the tumor microenvironment
(TME), few studies have mechanistically elucidated eosinophil functions in cancer …

The recognition of the immune system as a key component of the tumor microenvironment
(TME) led to promising therapeutics. Because such therapies benefit only subsets of …