Considerations for the use of phage therapy in clinical practice

GA Suh, TP Lodise, PD Tamma… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Increasing antimicrobial resistance and medical device-related infections have led to a
renewed interest in phage therapy as an alternative or adjunct to conventional …

Interaction between microbiota and immunity in health and disease

D Zheng, T Liwinski, E Elinav - Cell research, 2020 - nature.com
The interplay between the commensal microbiota and the mammalian immune system
development and function includes multifold interactions in homeostasis and disease. The …

The infant gut virome is associated with preschool asthma risk independently of bacteria

C Leal Rodríguez, SA Shah, MA Rasmussen… - Nature Medicine, 2024 - nature.com
Bacteriophage (also known as phage) communities that inhabit the gut have a major effect
on the structure and functioning of bacterial populations, but their roles and association with …

The safety and toxicity of phage therapy: a review of animal and clinical studies

D Liu, JD Van Belleghem, CR de Vries, E Burgener… - Viruses, 2021 - mdpi.com
Increasing rates of infection by antibiotic resistant bacteria have led to a resurgence of
interest in bacteriophage (phage) therapy. Several phage therapy studies in animals and …

In vivo hitchhiking of immune cells by intracellular self-assembly of bacteria-mimetic nanomedicine for targeted therapy of melanoma

C Gao, Q Wang, J Li, CHT Kwong, J Wei, B Xie… - Science …, 2022 - science.org
Cell-based drug carriers are mostly prepared in vitro, which may negatively affect the
physiological functions of cells, and induce possible immune rejections when applied to …

Insights in the development and uses of alternatives to antibiotic growth promoters in poultry and swine production

MRT Rahman, I Fliss, E Biron - Antibiotics, 2022 - mdpi.com
The overuse and misuse of antibiotics has contributed to the rise and spread of multidrug-
resistant bacteria. To address this global public health threat, many countries have restricted …

Fighting antibiotic resistance in hospital-acquired infections: current state and emerging technologies in disease prevention, diagnostics and therapy

E Avershina, V Shapovalova, G Shipulin - Frontiers in microbiology, 2021 - frontiersin.org
Rising antibiotic resistance is a global threat that is projected to cause more deaths than all
cancers combined by 2050. In this review, we set to summarize the current state of antibiotic …

Standardized bacteriophage purification for personalized phage therapy

T Luong, AC Salabarria, RA Edwards, DR Roach - Nature protocols, 2020 - nature.com
The world is on the cusp of a post-antibiotic era, but researchers and medical doctors have
found a way forward—by looking back at how infections were treated before the advent of …

A compendium of viruses from methanogenic archaea reveals their diversity and adaptations to the gut environment

S Medvedeva, G Borrel, M Krupovic, S Gribaldo - Nature Microbiology, 2023 - nature.com
Methanogenic archaea are major producers of methane, a potent greenhouse gas and
biofuel, and are widespread in diverse environments, including the animal gut. The …

[HTML][HTML] New insights into intestinal phages

R Sausset, MA Petit, V Gaboriau-Routhiau… - Mucosal …, 2020 - Elsevier
The intestinal microbiota plays important roles in human health. This last decade, the viral
fraction of the intestinal microbiota, composed essentially of phages that infect bacteria …