Alzheimer's disease (AD) is a multifactorial complex disease. The pathogenesis of AD is
very complicated, and involves the β-amyloid (Aβ) cascade, tau hyperphosphorylation …

Alzheimer's disease (AD) is a neurodegenerative disorder with progressive damage to brain
cells. It is the leading cause of dementia worldwide that is characterized by impairment of …

Alzheimer's disease is the most common type of dementia in the aging population
worldwide. The etiology and treatment of Alzheimer's disease are still not very clear. Finding …

Recently, formaldehyde (FA), existing in a number of different cells including neural cells,
was found to affect age-related cognitive impairment. Oral administration of methanol (the …

EPS15 and its homologous EPS15L1 are endocytic accessory proteins. Studies in
mammalian cell lines suggested that EPS15 and EPS15L1 regulate endocytosis in a …

Both Docosahexaenoic acid (DHA) and Phosphatidylcholine (PC) have been shown to halt
the pathogenesis of Alzheimer disease (AD) and vascular dementia. This study aimed to …

Oxytocin (OT) is a neuropeptide that primarily functions as a hormone controlling female
reproductive processes. Since numerous recent studies have shown that single and …

Objective To investigate the neuroprotective effects of icariin on formaldehyde (FA)-treated
human neuroblastoma SH-SY5Y cells and the possible mechanisms involved. Methods SH …

Levetiracetam is a homologue of piracetam with an a-ethyl side-chain substitution and it is a
Food and Drug Administration (FDA) approved antiepileptic drug. Recently, several studies …

γ-secretase is a membrane-embedded aspartyl protease carrying out cleavage of more than
100 single transmembrane-spanning proteins, including APP, Notch, N-cadherin, etc. Its …