The microcirculation is a complex and integrated system that supplies and distributes
oxygen throughout the tissues. The red blood cell (RBC) facilitates convective oxygen …

This review paper attempts to provide an overview of the principles and techniques that are
often termed electron paramagnetic resonance (EPR) oximetry. The paper discusses the …

Background Sepsis is a highly lethal disorder. Organ dysfunction in sepsis is not defined as
a clinicopathological entity but rather by changes in clinical, physiological, or biochemical …

Liver sequestration, mainly resulting from the phagocytosis of mononuclear phagocyte
system (MPS) cells, is a long-standing barrier in nanoparticle delivery, which severely …

Hesperidin (HDN) is a flavanone glycoside abundantly found in citrus fruits. HDN has been
reported to possess significant activities against allergy, heammorrhoids, hormonal …

Hypoxia is defined as a decrease in available oxygen reaching the tissues of the body. It is
linked to the pathology of cancer, cardiovascular disease, and stroke, the leading causes of …

AIM: To determine end-stage pathologic changes in the liver of septic patients dying in the
intensive care unit. METHODS: Needle liver biopsies obtained immediately after death from …

The present study is aimed at investigating the effect of curcumin (CMN) in salvaging
endotoxin-induced hepatic dysfunction and oxidative stress in the liver of rodents …

The lack of efficacy of anti-inflammatory drugs, anti-coagulants, anti-oxidants, etc. in critically
ill patients has shifted interest towards developing alternative treatments. Since inhibitors of …

Tissue oxygen tension is the partial pressure of oxygen within the interstitial space of an
organ bed. As it represents the balance between local oxygen delivery and consumption at …