Synthetic biology: bottom-up assembly of molecular systems
The bottom-up assembly of biological and chemical components opens exciting
opportunities to engineer artificial vesicular systems for applications with previously unmet …
opportunities to engineer artificial vesicular systems for applications with previously unmet …
[HTML][HTML] Proton gradients from light-harvesting E. coli control DNA assemblies for synthetic cells
K Jahnke, N Ritzmann, J Fichtler, A Nitschke… - Nature …, 2021 - nature.com
Bottom-up and top-down approaches to synthetic biology each employ distinct
methodologies with the common aim to harness living systems. Here, we realize a strategic …
methodologies with the common aim to harness living systems. Here, we realize a strategic …
Encapsulation of cannabidiol in oil-in-water nanoemulsions and nanoemulsion-filled hydrogels: a structure and biological assessment study
S Demisli, E Galani, M Goulielmaki, FL Kyrilis… - Journal of Colloid and …, 2023 - Elsevier
Hypothesis Lipophilic cannabidiol can be solubilized in oil-in water nanoemulsions, which
can then be impregnated into chitosan hydrogels forming another colloidal system that will …
can then be impregnated into chitosan hydrogels forming another colloidal system that will …
Polymeric Giant Unilamellar Vesicles with Integrated DNA‐Origami Nanopores: An Efficient Platform for Tuning Bioreaction Dynamics Through Controlled Molecular …
R Cochereau, V Maffeis, EC Dos Santos… - Advanced Functional …, 2023 - Wiley Online Library
Giant unilamellar vesicles (GUVs) are microcompartments serving to confine reactions,
allow signaling pathways, or design synthetic cells. Polymer GUVs are composed of …
allow signaling pathways, or design synthetic cells. Polymer GUVs are composed of …
Interface engineering in multiphase systems toward synthetic cells and organelles: From soft matter fundamentals to biomedical applications
Synthetic cells have a major role in gaining insight into the complex biological processes of
living cells; they also give rise to a range of emerging applications from gene delivery to …
living cells; they also give rise to a range of emerging applications from gene delivery to …
Bottom-up synthesis of artificial cells: recent highlights and future challenges
I Ivanov, SL Castellanos, S Balasbas III… - Annual Review of …, 2021 - annualreviews.org
The bottom-up approach in synthetic biology aims to create molecular ensembles that
reproduce the organization and functions of living organisms and strives to integrate them in …
reproduce the organization and functions of living organisms and strives to integrate them in …
Increased efficiency of charge-mediated fusion in polymer/lipid hybrid membranes
N Marušič, L Otrin, J Rauchhaus… - Proceedings of the …, 2022 - National Acad Sciences
Due to their augmented properties, biomimetic polymer/lipid hybrid compartments are a
promising substitute for natural liposomes in multiple applications, but the protein-free fusion …
promising substitute for natural liposomes in multiple applications, but the protein-free fusion …
[HTML][HTML] En route to dynamic life processes by SNARE-mediated fusion of polymer and hybrid membranes
A variety of artificial cells springs from the functionalization of liposomes with proteins.
However, these models suffer from low durability without repair and replenishment …
However, these models suffer from low durability without repair and replenishment …
Current problems and future avenues in proteoliposome research
AM Amati, S Graf, S Deutschmann… - Biochemical Society …, 2020 - portlandpress.com
Membrane proteins (MPs) are the gatekeepers between different biological compartments
separated by lipid bilayers. Being receptors, channels, transporters, or primary pumps, they …
separated by lipid bilayers. Being receptors, channels, transporters, or primary pumps, they …