Multiple Sclerosis (MS) is a neuroinflammatory disorder, which is histopathologically
characterized by multifocal inflammatory demyelinating lesions affecting both the central …

Phenothiazines (PTZs) are an emerging group of molecules showing effectiveness toward
redox signaling and reduction of oxidative injury to cells, via the activation on Kelch‐like …

HMGB1 is a highly conserved, ubiquitous protein in eukaryotic cells. HMGB1 is normally
localized to the nucleus, where it acts as a chromatin associated non-histone binding …

Aim This study aims to investigate the hepatoprotective effect of the antipsychotic drug
trifluoperazine (TFP) against cyclophosphamide (CPA)-induced hepatic injury by exploring …

Objective (s): Multiple sclerosis (MS) is a chronic disease of the central nervous system
(CNS) and its cause is unknown. Several environmental and genetic factors may have roles …

Subarachnoid hemorrhage (SAH) can lead to damage to the myelin sheath in white matter.
Through classification and analysis of relevant research results, the discussion in this paper …

Abstract Aflatoxin B 1 (AFB 1) is known to inhibit growth, and inflict hepatic damage by
interfering with protein synthesis. Allicin, has been acknowledged as an efficacious …

Astrocytes play a pivotal role in maintaining brain homeostasis. Recent research has
highlighted the significance of palmitic acid (PA) in triggering pro-inflammatory pathways …

Introduction Demyelination is a key factor in axonal degeneration and neural loss, leading to
disability in multiple sclerosis (MS) patients. Transforming growth factor beta activated …

The cuprizone (CPZ)-induced demyelination model, an animal model of Multiple sclerosis
(MS), is characterized by demyelination and motor dysfunction due to microglial-mediated …