The placenta: a maternofetal interface

K O'Brien, Y Wang - Annual Review of Nutrition, 2023 - annualreviews.org
The placenta is the gatekeeper between the mother and the fetus. Over the first trimester of
pregnancy, the fetus is nourished by uterine gland secretions in a process known as …

Oxidative stress in malaria: potential benefits of antioxidant therapy

ARQ Gomes, N Cunha, ELP Varela… - International Journal of …, 2022 - mdpi.com
Malaria is an infectious disease and a serious public health problem in the world, with 3.3
billion people in endemic areas in 100 countries and about 200 million new cases each …

Brain iron metabolism, redox balance and neurological diseases

G Gao, L You, J Zhang, YZ Chang, P Yu - Antioxidants, 2023 - mdpi.com
The incidence of neurological diseases, such as Parkinson's disease, Alzheimer's disease
and stroke, is increasing. An increasing number of studies have correlated these diseases …

Dietary approaches to iron deficiency prevention in childhood—a critical public health issue

JP Chouraqui - Nutrients, 2022 - mdpi.com
Iron is an essential nutrient, and individual iron status is determined by the regulation of iron
absorption, which is driven by iron requirements. Iron deficiency (ID) disproportionately …

The interaction between psychological stress and iron status on early-life neurodevelopmental outcomes

BM Reid, MK Georgieff - Nutrients, 2023 - mdpi.com
This review presents evidence from animal and human studies demonstrating the possible
connection and significant impact of poor iron status and psychological distress on …

Mitochondria at work: new insights into regulation and dysregulation of cellular energy supply and metabolism

V Schirrmacher - Biomedicines, 2020 - mdpi.com
Mitochondria are of great relevance to health, and their dysregulation is associated with
major chronic diseases. Research on mitochondria—156 brand new publications from 2019 …

Iron deposition in brain: does aging matter?

E Ficiarà, I Stura, C Guiot - International Journal of Molecular Sciences, 2022 - mdpi.com
The alteration of iron homeostasis related to the aging process is responsible for increased
iron levels, potentially leading to oxidative cellular damage. Iron is modulated in the Central …

Prognostic performance of hematological and serum iron and metabolite indices for detection of early iron deficiency induced metabolic brain dysfunction in infant …

BJ Sandri, J Kim, GR Lubach, EF Lock… - The Journal of …, 2024 - Elsevier
Background The current pediatric practice of monitoring for infantile iron deficiency (ID) via
hemoglobin (Hgb) screening at one y of age does not identify preanemic ID nor protect …

Ironing out mechanisms of iron homeostasis and disorders of iron deficiency

N Koleini, JS Shapiro, J Geier… - The Journal of clinical …, 2021 - Am Soc Clin Investig
Iron plays an important role in mammalian physiological processes. It is a critical component
for the function of many proteins, including enzymes that require heme and iron-sulfur …

Perineuronal nets and metal cation concentrations in the microenvironments of fast-spiking, parvalbumin-expressing GABAergic interneurons: relevance to …

JA Burket, JD Webb, SI Deutsch - Biomolecules, 2021 - mdpi.com
Because of their abilities to catalyze generation of toxic free radical species, free
concentrations of the redox reactive metals iron and copper are highly regulated …