A review of hemolysis prediction models for computational fluid dynamics

H Yu, S Engel, G Janiga, D Thévenin - Artificial organs, 2017 - Wiley Online Library
Flow‐induced hemolysis is a crucial issue for many biomedical applications; in particular, it
is an essential issue for the development of blood‐transporting devices such as left …

Device-induced hemostatic disorders in mechanically assisted circulation

S Wang, BP Griffith, ZJ Wu - Clinical and Applied …, 2021 - journals.sagepub.com
Mechanically assisted circulation (MAC) sustains the blood circulation in the body of a
patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) or on ventricular …

Fluid dynamics in the HeartMate 3: influence of the artificial pulse feature and residual cardiac pulsation

L Wiegmann, B Thamsen, D De Zélicourt… - Artificial …, 2019 - Wiley Online Library
Ventricular assist devices (VADs), among which the HeartMate 3 (HM3) is the latest clinically
approved representative, are often the therapy of choice for patients with end‐stage heart …

Multi-indicator analysis of mechanical blood damage with five clinical ventricular assist devices

Y Li, H Wang, Y Xi, A Sun, X Deng, Z Chen… - Computers in biology and …, 2022 - Elsevier
Purpose Device-induced blood damage contributes the hemolysis, thrombosis and bleeding
complications in patients supported with ventricular assist device (VAD). This study aims to …

Blood pump design variations and their influence on hydraulic performance and indicators of hemocompatibility

L Wiegmann, S Boës, D de Zélicourt… - Annals of biomedical …, 2018 - Springer
Patients with ventricular assist devices still suffer from high rates of adverse events. Since
many of these complications are linked to the flow field within the pump, optimization of the …

Investigation of hemocompatibility and vortical structures for a centrifugal blood pump based on large-eddy simulation

Y Liu, N Xie, Y Tang, Y Zhang - Physics of Fluids, 2022 - pubs.aip.org
The evolution of complex flow structures has a large impact on the hemocompatibility of the
centrifugal blood pump. In this study, the hemodynamic performance and the …

Investigation of the influence of blade configuration on the hemodynamic performance and blood damage of the centrifugal blood pump

Y Li, J Yu, H Wang, Y Xi, X Deng, Z Chen… - Artificial …, 2022 - Wiley Online Library
Purpose The design and optimization of centrifugal blood pumps are crucial for improved
extracorporeal membrane oxygenation system performance. Secondary flow passages are …

Computational characterization of flow and blood damage potential of the new maglev CH-VAD pump versus the HVAD and HeartMate II pumps

J Zhang, Z Chen, BP Griffith… - The International journal …, 2020 - journals.sagepub.com
Left ventricular assist devices are routinely used to treat patients with advanced heart failure
as a bridge to transplant or a destination therapy. However, non-physiological shear stress …

Flow features and device‐induced blood trauma in CF‐VADs under a pulsatile blood flow condition: a CFD comparative study

Z Chen, SK Jena, GA Giridharan… - … journal for numerical …, 2018 - Wiley Online Library
In this study, the flow features and device‐associated blood trauma in 4 clinical ventricular
assist devices (VADs; 2 implantable axial VADs, 1 implantable centrifugal VAD, and 1 …

Hemocompatibility and hemodynamic comparison of two centrifugal LVADs: HVAD and HeartMate3

A Gil, R Navarro, P Quintero, A Mares - Biomechanics and Modeling in …, 2023 - Springer
Mechanical circulatory support using ventricular assist devices is a common technique for
treating patients suffering from advanced heart failure. The latest generation of devices is …