Optical spectroscopy for in vivo medical diagnosis—a review of the state of the art and future perspectives
When light is incident to a biological tissue surface, combinations of optical processes occur,
such as reflection, absorption, elastic and non-elastic scattering, and fluorescence. Analysis …
such as reflection, absorption, elastic and non-elastic scattering, and fluorescence. Analysis …
Intravascular optical imaging technology for investigating the coronary artery
MJ Suter, SK Nadkarni, G Weisz, A Tanaka… - JACC: Cardiovascular …, 2011 - jacc.org
There is an ever-increasing demand for new imaging methods that can provide additional
information about the coronary wall to better characterize and stratify high-risk plaques, and …
information about the coronary wall to better characterize and stratify high-risk plaques, and …
Mesoscopic fluorescence lifetime imaging: Fundamental principles, clinical applications and future directions
Fluorescence lifetime imaging (FLIm) is an optical spectroscopic imaging technique capable
of real‐time assessments of tissue properties in clinical settings. Label‐free FLIm is sensitive …
of real‐time assessments of tissue properties in clinical settings. Label‐free FLIm is sensitive …
Fluorescence lifetime imaging microscopy: in vivo application to diagnosis of oral carcinoma
Y Sun, J Phipps, DS Elson, H Stoy, S Tinling, J Meier… - Optics letters, 2009 - opg.optica.org
A compact clinically compatible fluorescence lifetime imaging microscopy (FLIM) system
was designed and built for intraoperative disease diagnosis and validated in vivo in a …
was designed and built for intraoperative disease diagnosis and validated in vivo in a …
Design and evaluation of a device for fast multispectral time-resolved fluorescence spectroscopy and imaging
DR Yankelevich, D Ma, J Liu, Y Sun, Y Sun… - Review of Scientific …, 2014 - pubs.aip.org
The application of time-resolved fluorescence spectroscopy (TRFS) to in vivo tissue
diagnosis requires a method for fast acquisition of fluorescence decay profiles in multiple …
diagnosis requires a method for fast acquisition of fluorescence decay profiles in multiple …
Fluorescence lifetime spectroscopy for guided therapy of brain tumors
This study evaluates the potential of time-resolved laser induced fluorescence spectroscopy
(TR-LIFS) as intra-operative tool for the delineation of brain tumor from normal brain. Forty …
(TR-LIFS) as intra-operative tool for the delineation of brain tumor from normal brain. Forty …
Intraoperative delineation of primary brain tumors using time-resolved fluorescence spectroscopy
The goal of this study is to determine the potential of time-resolved laser-induced
fluorescence spectroscopy (TR-LIFS) as an adjunctive tool for delineation of brain tumor …
fluorescence spectroscopy (TR-LIFS) as an adjunctive tool for delineation of brain tumor …
Detection of rupture-prone atherosclerotic plaques by time-resolved laser-induced fluorescence spectroscopy
OBJECTIVE: Plaque with dense inflammatory cells, including macrophages, thin fibrous cap
and superficial necrotic/lipid core is thought to be prone-to-rupture. We report a time …
and superficial necrotic/lipid core is thought to be prone-to-rupture. We report a time …
256× 2 SPAD line sensor for time resolved fluorescence spectroscopy
We present a CMOS chip 256× 2 single photon avalanche diode (SPAD) line sensor, 23.78
µm pitch, 43.7% fill factor, custom designed for time resolved emission spectroscopy (TRES) …
µm pitch, 43.7% fill factor, custom designed for time resolved emission spectroscopy (TRES) …
Multimodal in vivo imaging of oral cancer using fluorescence lifetime, photoacoustic and ultrasound techniques
H Fatakdawala, S Poti, F Zhou, Y Sun, J Bec… - Biomedical optics …, 2013 - opg.optica.org
This work reports a multimodal system for label-free tissue diagnosis combining
fluorescence lifetime imaging (FLIm), ultrasound backscatter microscopy (UBM), and …
fluorescence lifetime imaging (FLIm), ultrasound backscatter microscopy (UBM), and …