Phytochemicals as inhibitors of NF-κB for treatment of Alzheimer's disease

EJ Seo, N Fischer, T Efferth - Pharmacological research, 2018 - Elsevier
Alzheimer's disease (AD) is the most prevalent form of dementia. The exact pathophysiology
of this disease remains incompletely understood and safe and effective therapies are …

[HTML][HTML] Watermelon lycopene and allied health claims

A Naz, MS Butt, MT Sultan, MMN Qayyum, RS Niaz - EXCLI journal, 2014 - ncbi.nlm.nih.gov
Presently, functional foods and nutraceuticals are gaining immense importance in the
prevention of various maladies through dietary regimen module. Consumption of fruits and …

Lycopene abrogates Aβ (1–42)-mediated neuroinflammatory cascade in an experimental model of Alzheimer's disease

AK Sachdeva, K Chopra - The Journal of nutritional biochemistry, 2015 - Elsevier
Background Neuroinflammation characterized by glial activation and release of
proinflammatory mediators is considered to play a critical role in the pathogenesis of …

Supplementation of lycopene attenuates lipopolysaccharide-induced amyloidogenesis and cognitive impairments via mediating neuroinflammation and oxidative …

J Wang, L Li, Z Wang, Y Cui, X Tan, T Yuan… - The Journal of nutritional …, 2018 - Elsevier
Neuroinflammation is documented to be the major culprit of Alzheimer's disease. Lycopene
(LYC), a fat soluble carotenoid, exhibits neuroprotective function in several …

A short overview of changes in inflammatory cytokines and oxidative stress in response to physical activity and antioxidant supplementation

S Taherkhani, K Suzuki, L Castell - Antioxidants, 2020 - mdpi.com
Excessive release of inflammatory cytokines and oxidative stress (OS) are triggering factors
in the onset of chronic diseases. One of the factors that can ensure health in humans is …

Are the health attributes of lycopene related to its antioxidant function?

JW Erdman Jr, NA Ford, BL Lindshield - Archives of biochemistry and …, 2009 - Elsevier
A variety of epidemiological trials have suggested that higher intake of lycopene-containing
foods (primarily tomato products) or blood lycopene concentrations are associated with …

Lycopene attenuates di (2-ethylhexyl) phthalate-induced mitophagy in spleen by regulating the sirtuin3-mediated pathway

XY Dai, Y Zhao, J Ge, SY Zhu, MZ Li, M Talukder… - Food & Function, 2021 - pubs.rsc.org
Lycopene (Lyc) has been discussed as a potential effector in the prevention and therapy of
various diseases. Di (2-ethylhexyl) phthalate (DEHP) is regarded as a universal …

[HTML][HTML] Carotenoids: Therapeutic strategy in the battle against viral emerging diseases, COVID-19: An overview

A Khalil, D Tazeddinova, K Aljoumaa… - … nutrition and food …, 2021 - ncbi.nlm.nih.gov
Carotenoids, a group of phytochemicals, are naturally found in the Plant kingdom,
particularly in fruits, vegetables, and algae. There are more than 600 types of carotenoids …

Lycopene attenuates diabetes-associated cognitive decline in rats

A Kuhad, R Sethi, K Chopra - Life sciences, 2008 - Elsevier
Diabetes-induced learning and memory impairment, characterized by impaired cognitive
functions and neurochemical and structural abnormalities, involve direct neuronal damage …

Endurance exercise causes mitochondrial and oxidative stress in rat liver: effects of a combination of mitochondrial targeting nutrients

L Sun, W Shen, Z Liu, S Guan, J Liu, S Ding - Life sciences, 2010 - Elsevier
AIMS: Endurance exercise causes fatigue due to mitochondrial dysfunction and oxidative
stress. In order to find an effective strategy to prevent fatigue or enhance recovery, the effects …