Evolution of orbitrap mass spectrometry instrumentation
S Eliuk, A Makarov - Annual review of analytical chemistry, 2015 - annualreviews.org
We discuss the evolution of OrbitrapTM mass spectrometry (MS) from its birth in the late
1990s to its current role as one of the most prominent techniques for MS. The Orbitrap mass …
1990s to its current role as one of the most prominent techniques for MS. The Orbitrap mass …
Non-model organisms, a species endangered by proteogenomics
J Armengaud, J Trapp, O Pible, O Geffard… - Journal of …, 2014 - Elsevier
Previously, large-scale proteomics was possible only for organisms whose genomes were
sequenced, meaning the most common model organisms. The use of next-generation …
sequenced, meaning the most common model organisms. The use of next-generation …
Unification of protein abundance datasets yields a quantitative Saccharomyces cerevisiae proteome
Protein activity is the ultimate arbiter of function in most cellular pathways, and protein
concentration is fundamentally connected to protein action. While the proteome of yeast has …
concentration is fundamentally connected to protein action. While the proteome of yeast has …
The one hour yeast proteome
We describe the comprehensive analysis of the yeast proteome in just over one hour of
optimized analysis. We achieve this expedited proteome characterization with improved …
optimized analysis. We achieve this expedited proteome characterization with improved …
Integrated analysis of shotgun proteomic data with PatternLab for proteomics 4.0
PatternLab for proteomics is an integrated computational environment that unifies several
previously published modules for the analysis of shotgun proteomic data. The contained …
previously published modules for the analysis of shotgun proteomic data. The contained …
Novel parallelized quadrupole/linear ion trap/Orbitrap tribrid mass spectrometer improving proteome coverage and peptide identification rates
Proteome coverage and peptide identification rates have historically advanced in line with
improvements to the detection limits and acquisition rate of the mass spectrometer. For a …
improvements to the detection limits and acquisition rate of the mass spectrometer. For a …
Quantitative mass spectrometry-based multiplexing compares the abundance of 5000 S. cerevisiae proteins across 10 carbon sources
The budding yeast Saccharomyces cerevisiae is a model system for investigating biological
processes. Cellular events are known to be dysregulated due to shifts in carbon sources …
processes. Cellular events are known to be dysregulated due to shifts in carbon sources …
The proteomic landscape of genome-wide genetic perturbations
Functional genomic strategies have become fundamental for annotating gene function and
regulatory networks. Here, we combined functional genomics with proteomics by quantifying …
regulatory networks. Here, we combined functional genomics with proteomics by quantifying …
One-hour proteome analysis in yeast
Recent advances in chromatography and mass spectrometry (MS) have made rapid and
deep proteomic profiling possible. To maximize the performance of the recently produced …
deep proteomic profiling possible. To maximize the performance of the recently produced …
Middle-down approach: a choice to sequence and characterize proteins/proteomes by mass spectrometry
PB Pandeswari, V Sabareesh - RSC advances, 2019 - pubs.rsc.org
Owing to rapid growth in the elucidation of genome sequences of various organisms,
deducing proteome sequences has become imperative, in order to have an improved …
deducing proteome sequences has become imperative, in order to have an improved …