Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies

H Tian, T Zhang, S Qin, Z Huang, L Zhou, J Shi… - Journal of hematology & …, 2022 - Springer
Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …

[HTML][HTML] Advances in understanding the role of P-gp in doxorubicin resistance: Molecular pathways, therapeutic strategies, and prospects

S Mirzaei, MH Gholami, F Hashemi, A Zabolian… - Drug Discovery …, 2022 - Elsevier
Abstract P-glycoprotein (P-gp) is a drug efflux transporter that triggers doxorubicin (DOX)
resistance. In this review, we highlight the molecular avenues regulating P-gp, such as Nrf2 …

[HTML][HTML] Hyaluronic acid-based nanoplatforms for Doxorubicin: A review of stimuli-responsive carriers, co-delivery and resistance suppression

M Ashrafizadeh, S Mirzaei, MH Gholami… - Carbohydrate …, 2021 - Elsevier
An important motivation for the use of nanomaterials and nanoarchitectures in cancer
therapy emanates from the widespread emergence of drug resistance. Although doxorubicin …

Recent biomedical advancements in graphene oxide-and reduced graphene oxide-based nanocomposite nanocarriers

N Bellier, P Baipaywad, N Ryu, JY Lee… - Biomaterials …, 2022 - spj.science.org
Recently, nanocarriers, including micelles, polymers, carbon-based materials, liposomes,
and other substances, have been developed for efficient delivery of drugs, nucleotides, and …

Multifunctional gold nanoparticles in cancer diagnosis and treatment

Y Yang, X Zheng, L Chen, X Gong, H Yang… - International journal …, 2022 - Taylor & Francis
Cancer is the second leading cause of death in the world, behind only cardiovascular
diseases, and is one of the most serious diseases threatening human health nowadays …

Approved nanomedicine against diseases

Y Jia, Y Jiang, Y He, W Zhang, J Zou, KT Magar… - Pharmaceutics, 2023 - mdpi.com
Nanomedicine is a branch of medicine using nanotechnology to prevent and treat diseases.
Nanotechnology represents one of the most effective approaches in elevating a drug's …

Solar-Assisted, Fast, and In Situ Recovery of Crude Oil Spill by a Superhydrophobic and Photothermal Sponge

H Niu, J Li, X Wang, F Luo, Z Qiang… - ACS Applied Materials & …, 2021 - ACS Publications
Development of a functional sorbent for effective crude oil absorption is essential to address
large-scale spilling incidents. Herein, we demonstrate a facile method for preparing a …

Intelligent and spatiotemporal drug release based on multifunctional nanoparticle-integrated dissolving microneedle system for synergetic chemo-photothermal …

Y Zhao, Y Zhou, D Yang, X Gao, T Wen, J Fu, X Wen… - Acta Biomaterialia, 2021 - Elsevier
Cutaneous melanoma is one of the most common malignant skin cancer with high lethality.
Chemotherapy and photothermal therapy are important and extensively studied treatment …

Versatile types of polysaccharide-based drug delivery systems: From strategic design to cancer therapy

Y Sun, X Jing, X Ma, Y Feng, H Hu - International Journal of Molecular …, 2020 - mdpi.com
Chemotherapy is still the most direct and effective means of cancer therapy nowadays. The
proposal of drug delivery systems (DDSs) has effectively improved many shortcomings of …

A hyaluronic acid functionalized self-nano-emulsifying drug delivery system (SNEDDS) for enhancement in ciprofloxacin targeted delivery against intracellular …

R Arshad, TA Tabish, MH Kiani, IM Ibrahim, G Shahnaz… - Nanomaterials, 2021 - mdpi.com
Ciprofloxacin (CIP), a potent anti-bacterial agent of the fluroquinolone family, shows poor
solubility and permeability, thus leading to the development of intracellular pathogens …