Patients with pulmonary hypertension associated with congenital heart disease make up an
increasing proportion of the total pulmonary hypertension population who bring with them …

Since its introduction more than 35 years ago, gadolinium-enhanced MRI has fundamentally
changed medical practice. Although extraordinarily safe, gadolinium-based contrast agents …

Objectives Developing new high relaxivity gadolinium-based contrast agents (GBCAs) for
magnetic resonance imaging (MRI) allowing dose reduction while maintaining similar …

Background Gadopiclenol is a macrocyclic gadolinium-based contrast agent (GBCA) with
higher relaxivity compared with standard GBCAs, potentially allowing gadolinium dose …

Direct putaminal infusion of adeno-associated virus vector (serotype 2)(AAV2) containing
the human glial cell line-derived neurotrophic factor (GDNF) transgene was studied in a …

The last decades have seen increased concern about the possible effects of low to
moderate doses of ionizing radiation (IR) exposure on cognitive function. An interdisciplinary …

BACKGROUND. Radiologists have variable diagnostic performance and considerable
interreader variability when interpreting MR enterography (MRE) examinations for …

Myocardial fibrosis is recognized as a key pathological process in the development of
cardiac disease and a target for future therapeutics. Despite this recognition, the assessment …

Background Linear gadolinium-based contrast agents (GBCAs) are known to be retained at
higher levels of gadolinium than macro-cyclic GBCAs. However, very little is known …

Simple Summary Conventional imaging methods, such as ultrasonography, computed
tomography, and magnetic resonance imaging may be inadequate to accurately diagnose …