Anti-obesity drugs: past, present and future
RJ Rodgers, MH Tschöp… - Disease models & …, 2012 - journals.biologists.com
The ideal anti-obesity drug would produce sustained weight loss with minimal side effects.
The mechanisms that regulate energy balance have substantial built-in redundancy, overlap …
The mechanisms that regulate energy balance have substantial built-in redundancy, overlap …
Mechanisms of weight regain.
L Busetto, S Bettini, J Makaronidis, CA Roberts… - European journal of …, 2021 - Elsevier
Weight regain following weight loss is frequent problem that people with obesity face. This
weight recidivism is often attributed to the lack of compliance with appropriate food habits …
weight recidivism is often attributed to the lack of compliance with appropriate food habits …
A prospective open‐label trial of a CBD/THC cannabis oil in dravet syndrome
B McCoy, L Wang, M Zak, S Al‐Mehmadi… - Annals of Clinical …, 2018 - Wiley Online Library
Abstract Introduction Both Δ9 Tetrahydrocannabidiol (THC) and cannabidiol (CBD)
components of cannabis, have been shown to have anticonvulsant effects. Cannabis oils …
components of cannabis, have been shown to have anticonvulsant effects. Cannabis oils …
The antimicrobial activity of cannabinoids
JA Karas, LJM Wong, OKA Paulin, AC Mazeh… - Antibiotics, 2020 - mdpi.com
A post-antibiotic world is fast becoming a reality, given the rapid emergence of pathogens
that are resistant to current drugs. Therefore, there is an urgent need to discover new …
that are resistant to current drugs. Therefore, there is an urgent need to discover new …
[HTML][HTML] Lipids in psychiatric disorders and preventive medicine
M Schneider, B Levant, M Reichel, E Gulbins… - Neuroscience & …, 2017 - Elsevier
Psychiatric disorders like mood disorders, schizophrenia, or drug addiction affect a sizeable
proportion of the human population and severely compromise quality of life. Therefore …
proportion of the human population and severely compromise quality of life. Therefore …
CB1 cannabinoid receptors and their associated proteins
AC Howlett, LC Blume… - Current medicinal …, 2010 - ingentaconnect.com
CB1 receptors are G-protein coupled receptors (GPCRs) abundant in neurons, in which they
modulate neurotransmission. The CB1 receptor influence on memory and learning is well …
modulate neurotransmission. The CB1 receptor influence on memory and learning is well …
Cannabidiol attenuates the appetitive effects of Δ9-tetrahydrocannabinol in humans smoking their chosen cannabis
CJA Morgan, TP Freeman, GL Schafer… - …, 2010 - nature.com
Worldwide cannabis dependence is increasing, as is the concentration of Δ 9-
tetrahydrocannabinol (THC) in street cannabis. At the same time, the concentration of the …
tetrahydrocannabinol (THC) in street cannabis. At the same time, the concentration of the …
Effects of oral, smoked, and vaporized cannabis on endocrine pathways related to appetite and metabolism: a randomized, double-blind, placebo-controlled, human …
M Farokhnia, GR McDiarmid, MN Newmeyer… - Translational …, 2020 - nature.com
As perspectives on cannabis continue to shift, understanding the physiological and
behavioral effects of cannabis use is of paramount importance. Previous data suggest that …
behavioral effects of cannabis use is of paramount importance. Previous data suggest that …
Endocannabinoid modulation of homeostatic and non-homeostatic feeding circuits
The endocannabinoid system has emerged as a key player in the control of eating.
Endocannabinoids, including 2-arachidonoylglycerol (2-AG) and anandamide (AEA) …
Endocannabinoids, including 2-arachidonoylglycerol (2-AG) and anandamide (AEA) …
Ghrelin and food reward
Food intake is tightly regulated by homeostatic and reward mechanisms and the adequate
function of both is necessary for the proper maintenance of energy balance. Ghrelin impacts …
function of both is necessary for the proper maintenance of energy balance. Ghrelin impacts …