Evidence for a close bidirectional link between the brain and the gut has led to a paradigm
shift in neurology, especially in the case of Parkinson disease (PD), in which gastrointestinal …

The human body is full of an extensive number of commensal microbes, consisting of
bacteria, viruses, and fungi, collectively termed the human microbiome. The initial …

The gut microbiota is emerging as an important modulator of neurodegenerative diseases,
and accumulating evidence has linked gut microbes to Parkinson's disease (PD) …

The objectives of this review on 'leaky gut'for clinicians are to discuss the components of the
intestinal barrier, the diverse measurements of intestinal permeability, their perturbation in …

A pro-inflammatory intestinal microbiome is characteristic of Parkinson's disease (PD).
Prebiotic fibers change the microbiome and this study sought to understand the utility of …

Parkinson's disease is a chronic neurodegenerative disease characterized by the
accumulation of misfolded alpha-synuclein protein (Lewy bodies) in dopaminergic neurons …

Background PD may begin with the intestinal accumulation of α‐synuclein fibrils, which can
be causally associated with gut dysbiosis. The variability of gut microbiota across countries …

Abstract Background Patients with Parkinson's disease (PD) frequently have gastrointestinal
symptoms (eg constipation) and exhibit the PD-typical pathohistology in the enteric nervous …

The intestinal barrier, which primarily consists of a mucus layer, an epithelial barrier, and a
gut vascular barrier, has a crucial role in health and disease by facilitating nutrient …

Parkinson's disease (PD) is the second most common neurodegenerative disease
characterized by motor dysfunction. Growing evidence has demonstrated that gut dysbiosis …